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Researchers discover why cocaine is so addictive

Mount Sinai researchers have discovered how cocaine corrupts the brain and becomes addictive. These findings -- the first to connect activation of specific neurons to alterations in cocaine reward -- were published in Science on Oct ...

Medicine & Health / Medical research

created Oct 18, 2010 | popularity 4.8 / 5 (10) | comments 2 | with audio podcast

Brain-behavior disconnect in cocaine addiction

(PhysOrg.com) -- Parts of the brain involved in monitoring behaviors and emotions show different levels of activity in cocaine users relative to non-drug users, even when both groups perform equally well on ...

Medicine & Health / Neuroscience

created May 25, 2009 | popularity 4.4 / 5 (9) | comments 3

Wastewater clues to illicit drug use

A new chemical analysis of sewage is revealing more detailed information than ever about drug abuse trends.

Chemistry / Analytical Chemistry

created Mar 22, 2012 | popularity 4.5 / 5 (4) | comments 0 | with audio podcast

Senators target Internet narcotics

(AP) -- Two U.S. senators said Sunday they will ask federal authorities to crack down on a secretive narcotics market operated on the Internet with anonymous sales and untraceable currency.

Technology / Internet

created Jun 05, 2011 | popularity 1 / 5 (1) | comments 15

Cocaine images capture motivated attention among users

(PhysOrg.com) -- Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and Stony Brook University (SBU) have conducted the most comprehensive study to date of how cocaine users respond ...

Medicine & Health / Neuroscience

created Apr 04, 2011 | popularity not rated yet | comments 1 | with audio podcast

Vaccine blocks cocaine high in mice

Researchers have produced a lasting anti-cocaine immunity in mice by giving them a safe vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

Medicine & Health / Medical research

created Jan 04, 2011 | popularity 3.5 / 5 (2) | comments 0 | with audio podcast

Alcohol most harmful drug based on multicriteria analysis (Update)

(PhysOrg.com) -- A new system that ranks drugs on the basis of harm caused to both the user and others places alcohol as the most harmful drug, above heroin and crack. The scale, developed by drug experts led by Professor ...

Medicine & Health / Health

created Nov 01, 2010 | popularity 3.5 / 5 (13) | comments 12 | with audio podcast

Ritalin improves brain function, task performance in cocaine abusers

(PhysOrg.com) -- Brain-scanning study shows Ritalin improves impaired brain function in people addicted to cocaine, implying it could play a role in facilitating recovery from addiction.

Medicine & Health / Medical research

created Sep 07, 2010 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Researchers uncover step in brain events leading up to addiction

A regulatory protein best known for its role in a rare genetic brain disorder also may play a critical role in cocaine addiction, according to a recent study in rats, funded by the National Institute on Drug Abuse (NIDA), ...

Medicine & Health / Neuroscience

created Aug 15, 2010 | popularity 4.4 / 5 (8) | comments 3 | with audio podcast

Scientists uncover previously unknown natural mechanism that controls cocaine use

Scientists from The Scripps Research Institute have found that a particular type of genetic material plays a key role in determining vulnerability to cocaine addiction and may offer an entirely new direction for the development ...

Medicine & Health / Medical research

created Jul 07, 2010 | popularity 4.2 / 5 (5) | comments 1 | with audio podcast

Cocaine-related deaths rise in warm weather

Researchers in the United States have discovered that accidental overdose deaths involving cocaine rise when the average weekly ambient temperature passes 24 degrees Celsius (75 degrees Fahrenheit).

Medicine & Health / Other

created Mar 02, 2010 | popularity 3 / 5 (1) | comments 1 | with audio podcast

Sudden death in cocaine abusers: Study reveals the role played by the illegal drug

Forensic pathologists have shown that over three per cent of all sudden deaths in south-west Spain are related to the use of cocaine. They believe their findings can be extrapolated to much of the rest of Europe, indicating ...

Medicine & Health / Medical research

created Jan 13, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New mechanism underlying cocaine addiction discovered

Researchers have identified a key epigenetic mechanism in the brain that helps explain cocaine's addictiveness, according to research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes ...

Medicine & Health / Medical research

created Jan 07, 2010 | popularity 4 / 5 (2) | comments 0 | with audio podcast

A new ally in the battle against cocaine addiction

A recent study shows that a bacterial protein may help cocaine addicts break the habit.

Medicine & Health / Medical research

created Jan 02, 2010 | popularity 3.3 / 5 (4) | comments 2 | with audio podcast

Brain Scan Study Shows Cocaine Abusers Can Control Cravings

(PhysOrg.com) -- When asked to inhibit their response to a "cocaine-cues" video, active cocaine abusers were, on average, able to suppress activity in brain regions linked to drug craving, according to a new ...

Medicine & Health / Medical research

created Nov 30, 2009 | popularity 5 / 5 (1) | comments 0

Cocaine

Cocaine (benzoylmethylecgonine) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is both a stimulant of the central nervous system and an appetite suppressant. Specifically, it is a dopamine reuptake inhibitor, a norepinephrine reuptake inhibitor and a serotonin reuptake inhibitor, which mediates functionality of such as an exogenous DAT ligand. Because of the way it affects the mesolimbic reward pathway, cocaine is addictive.

Its possession, cultivation, and distribution are illegal for non-medicinal and non-government sanctioned purposes in virtually all parts of the world. Although its free commercialization is illegal and has been severely penalized in virtually all countries, its use worldwide remains widespread in many social, cultural, and personal settings.

For more information about Cocaine, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: brain , drug , neurons