News tagged with clopidogrel

Genetic variations linked with worse outcomes with use of antiplatelet drug for cardiac procedures

An analysis of data from previously published studies indicates that use of the antiplatelet drug clopidogrel for patients who have common genetic variants of a certain gene and are undergoing a procedure such as coronary ...

Medicine & Health / Medical research

created Oct 26, 2010 | popularity not rated yet | comments 0

Breakthrough in drug trial offers hope for heart attack patients

New findings from a major drug trial have brought experts a step closer to developing a drug which could prevent thousands of British deaths from heart attacks.

Medicine & Health / Medical research

created Sep 13, 2010 | popularity not rated yet | comments 0

Study contradicts reports of problems with blood-thinner

New findings by McMaster University researchers contradict earlier reports that people with a certain genetic make-up don't benefit from the blood-thinner clopidogrel, also known as Plavix.

Medicine & Health / Medications

created Aug 29, 2010 | popularity not rated yet | comments 0

Plavix may be treatment for dogs at risk of thromboembolic disease

Companion animals that have a long-term need for anticoagulant drug therapies may soon find help in a top-selling antiplatelet drug marketed to humans: clopidogrel, commonly known by the trade-name Plavix.

Biology / Other

created Jul 14, 2010 | popularity not rated yet | comments 0

Drug ads ineffective for boosting sales, could cost taxpayers: study

US Taxpayers may be on the hook for the high cost of drug advertising that does little to boost sales, according to a new study led by a University of British Columbia health policy researcher.

Medicine & Health / Health

created Nov 23, 2009 | popularity not rated yet | comments 0

How life-threatening blood clots take hold

When plaques coating blood vessel walls rupture and expose collagen, platelets spring into action to form a blood clot at the damaged site. Now, a new report in the April 17th issue of the journal Cell, a Cell Press public ...

Medicine & Health / Medical research

created Apr 16, 2009 | popularity not rated yet | comments 0

Patients may not have to stop taking anti-platelets for some surgeries

Despite the common clinical practice among surgeons to discontinue their patients' anti-platelet therapy prior to surgery, a recent study of patients undergoing carotid endarterectomy (CEA) indicated that this practice may ...

Medicine & Health / Other

created Dec 09, 2010 | popularity not rated yet | comments 0

Study examines risk of bleeding among patients taking 2 anti-platelet drugs

treatment with the medications clopidogrel and aspirin together to prevent blood clots—poses a clinically significant risk of hemorrhage that should be considered before prescribing, according to a report in the November ...

Medicine & Health / Medical research

created Nov 22, 2010 | popularity not rated yet | comments 0

Eliminating or reducing cost-sharing for high-value prescription drugs improves medication use

An initiative by the U. S. technology company Pitney Bowes to make medications of proven value less expensive for their employees succeeded in stabilizing employees' adherence to their treatment regimens, according to a Commonwealth ...

Medicine & Health / Health

created Nov 02, 2010 | popularity not rated yet | comments 0

Aspirin use associated with lower risk of cancer death for men with prostate cancer

Men with prostate cancer who take anticoagulants like aspirin in addition to radiation therapy or surgery may be able to cut their risk of dying of the disease by more than half, according to a large study presented on November ...

Medicine & Health / Cancer

created Oct 25, 2010 | popularity 5 / 5 (2) | comments 0

Treating metabolic syndrome, undergoing carotid angioplasty

Treating metabolic syndrome and undergoing carotid angioplasty may prevent recurrent stroke or transient ischemic attack (TIA), according to revised American Heart Association/American Stroke Association guidelines.

Medicine & Health / Diseases, Conditions, Syndromes

created Oct 21, 2010 | popularity not rated yet | comments 0

Study examines use of stent with bioabsorbable polymer

Three-year data demonstrated that satisfactory clinical and safety outcomes of sirolimus eluting stents with a biodegradable polymer were sustained in a real world setting. The results were presented at the 22nd annual Transcatheter ...

Medicine & Health / Medical research

created Sep 21, 2010 | popularity not rated yet | comments 0

Genetic variation in key cell pumping mechanism reduces effects of clopidogrel treatment

A study published Online First and in an upcoming Lancet shows that patients with a genetic variation affecting a key protein pump in drug transport do not respond as well to the anticlotting drug clopidogrel—as such, patien ...

Medicine & Health / Medical research

created Aug 29, 2010 | popularity not rated yet | comments 0

Ticagrelor is better than clopidogrel to prevent blood clots regardless of genetic profile

A study published Online First and in an upcoming Lancet shows that anticlotting treatment using ticagrelor is better than clopidogrel, regardless of the presence of genetic variations that leads to variable efficacy of clo ...

Medicine & Health / Medical research

created Aug 29, 2010 | popularity not rated yet | comments 0

First study examines postpolypectomy bleeding in colonoscopy patients on uninterrupted clopidogrel

Researchers at the Syracuse Veterans Affairs Medical Center in New York examined postpolypectomy bleeding in patients undergoing colonoscopy on uninterrupted clopidogrel and found that the postpolypectomy bleeding rate is ...

Medicine & Health / Medical research

created May 19, 2010 | popularity not rated yet | comments 0

Clopidogrel

Clopidogrel is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix. The drug works by irreversibly inhibiting a receptor called P2Y12, an adenosine diphosphate ADP chemoreceptor. Adverse effects include hemorrhage, severe neutropenia, and thrombotic thrombocytopenic purpura (TTP).

For more information about Clopidogrel, read the full article at Wikipedia.
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