News tagged with cisplatin
'Copper pump's' potential benefit in cancer treatment
(Phys.org) -- A team of University of California, San Diego researchers has made new discoveries about a copper-transporting protein in the membranes of human cells that drug-discovery scientists can co-opt ...
May 17, 2012 |
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Gold used as safe driver of cancer drug
(PhysOrg.com) -- Gold nanoparticles can be used as delivery vehicles for platinum anticancer drugs, improving targeting and uptake into cells, according to research published in this month's edition of the ...
Nanotechnology / Bio & Medicine
Mar 21, 2012 |
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Cancer drug cisplatin found to bind like glue in cellular RNA
An anti-cancer drug used extensively in chemotherapy binds pervasively to RNA -- up to 20-fold more than it does to DNA, a surprise finding that suggests new targeting approaches might be useful, according to University of ...
Nov 21, 2011 |
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Inhaled nanoparticles deliver potent anticancer cocktail to lung tumors and block resistance
(PhysOrg.com) -- An ideal treatment for lung cancer would be one that could be inhaled deep into lung tissue where it would deliver tumor-killing agents that would then largely stay in the lungs, avoiding the toxicities that ...
Nanotechnology / Bio & Medicine
Nov 21, 2011 |
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Cancer cell survival is not 'miR-ly' dependent on p53
Squamous cell carcinoma (SCC) is a common type of skin cancer. In this paper, Leif Ellisen and colleagues at Mass General Hospital investigated the p53-related proteins p63 and p73 in SCC cells, and discovered a feedback ...
Jan 10, 2011 |
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Nanoparticles deliver one-two therapeutic punch to kill tumor cells
The standard approach to cancer therapy today is to mix and match chemotherapy drugs in order to attack tumors in multiple ways. Now, two separate teams of investigators have demonstrated that using nanoparticles to deliver ...
Nanotechnology / Bio & Medicine
Dec 17, 2010 |
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New treatment to overpower drug resistance in ovarian cancer
Drug resistance is a major obstacle in curing ovarian cancer but new research from the Centenary Institute has discovered a treatment that kills ovarian cancer cells in a new way that can break the resistance mechanism. ...
Nov 15, 2010 |
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Israel's scientists think big with the very, very small
A material just one atom thick that is stronger than steel but flexes like rubber. A "mini-submarine" that can trick the immune system and deliver a payload of chemotherapy deep inside a tumour.
Nanotechnology / Nanomaterials
Nov 09, 2010 |
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Nanoparticles deliver combination chemotherapy directly to prostate cancer cells
In recent years, studies have shown that for many types of cancer, combination drug therapy is more effective than single drugs. However, it is usually difficult to get the right amount of each drug to the tumor. Now, researchers ...
Nanotechnology / Bio & Medicine
Oct 27, 2010 |
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Major component in turmeric enhance effect of chemotherapy drug in head and neck cancer
Curcumin, the major component in the spice turmeric, when combined with the drug Cisplatin enhances the chemotherapy's suppression of head and neck cancer cell growth, researchers with UCLA's Jonsson Cancer Center have found.
Oct 19, 2010 |
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Breakthrough: With a chaperone, copper breaks through
(PhysOrg.com) -- Information on proteins is critical for understanding how cells function in health and disease. But while regular proteins are easy to extract and study, it is far more difficult to gather ...
Oct 18, 2010 |
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Adding cetuximab to chemotherapy doubles response rate in hard-to-treat breast cancer
European researchers have proven for the first time that targeting the epidermal growth factor receptor can provide substantial clinical benefit for women with hard-to-treat triple-negative breast cancer.
Oct 12, 2010 |
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Adding topotecan to standard treatment for ovarian cancer does not improve progression-free survival
Adding topotecan to carboplatin plus paclitaxel, the standard treatment for ovarian cancer, does not improve progression-free survival in patients and leads to greater toxicity, according to a study published online October ...
Oct 11, 2010 |
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Elucidating side effects of antineoplastic agent
Cisplatin, an anticancer drug widely used for treating various types of tumor, can induce side effects in the short term. A team of French scientists, mostly from CNRS and the Universite de Nice has provided first in vitro ...
Oct 06, 2010 |
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Platinum and light together fight cancer
(PhysOrg.com) -- Researchers continue to search for cancer treatments that effectively destroy tumor cells while protecting surrounding healthy tissue and the body. One intriguing approach involves photoactivated ...
Sep 14, 2010 |
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Cisplatin
Cisplatin, cisplatinum, or cis-diamminedichloroplatinum(II) (CDDP) (trade names Platinol and Platinol-AQ) is a chemotherapy drug. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, and germ cell tumors. It was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
For more information about Cisplatin, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
