News tagged with chromosome breakage
How yeast chromosomes avoid the bad breaks
The human genome is peppered with repeated DNA elements that can vary from a few to thousands of consecutive copies of the same sequence. During meiosis—the cell division that produces sperm and eggs—repetitive ...
Aug 07, 2011 |
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Chromosome breakpoints contribute to genetic variation
A new study reveals that - contrary to decades of evolutionary thought - chromosome regions that are prone to breakage when new species are formed are a rich source of genetic variation.
Apr 23, 2009 |
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Search results for chromosome breakage
The proteins ensuring genome protection
Researchers from the University of Geneva (UNIGE), Switzerland, have discovered the crucial role of two proteins in developing a cell 'anti-enzyme shield'. This protection system, which operates at the level of molecular ...
Feb 12, 2012 |
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New light shed on chromosome fragility
Why are certain chromosome regions prone to breakages? The answer is crucial, as this fragility is involved in the development of tumors. A team from the Institut de Génétique et de Biologie Moleculaire et Cellulaire ...
Dec 26, 2011 |
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The machinery for recombination is part of the chromosome structure
During the development of gametes, such as egg and sperm cells in humans, chromosomes are broken and rearranged at many positions. Using state of the art technology, the research group of Franz Klein, professor for genetics ...
Aug 09, 2011 |
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Chromosome number changes in yeast
Researchers from Trinity College Dublin have uncovered the evolutionary mechanisms that have caused increases or decreases in the numbers of chromosomes in a group of yeast species during the last 100-150 million years. The ...
Jul 21, 2011 |
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Genomic fault zones come and go
The fragile regions in mammalian genomes that are thought to play a key role in evolution go through a "birth and death" process, according to new bioinformatics research performed at the University of California, ...
Nov 30, 2010 |
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New studies explain how cancer cells 'eat us alive'
Four key studies now propose a new theory about how cancer cells grow and survive, allowing researchers to design better diagnostics and therapies to target high-risk cancer patients. These studies were conducted by a large ...
Sep 01, 2010 |
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Researchers find new translocation; weak spots in DNA lead to genetic disease
A genetics research team based at The Children's Hospital of Philadelphia continues to discover recurrent translocations—places in which two chromosomes exchange pieces of themselves. As many as 1 in 600 persons carry balanced ...
Jul 29, 2010 |
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Cells of Aggressive Leukemia Hijack Normal Protein to Grow
(PhysOrg.com) -- Researchers have found that one particularly aggressive type of blood cancer, mixed lineage leukemia (MLL), has an unusual way to keep the molecular motors running. The cancer cells rely on ...
Feb 25, 2010 |
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Sorting the drivers from the passengers in the cancer genome
A new study of mutations in cancer genomes shows how researchers can begin to distinguish the 'driver' mutations that push cells towards cancer from the 'passenger' mutations that are a by-product of cancer cell development. ...
Feb 17, 2010 |
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'Blindfold handshake' in the cell prevents diseases
(PhysOrg.com) -- Researchers at the University of Dundee, UK, have made a significant new discovery about how cells behave and protect themselves against cancers and genetic disorders.
Feb 17, 2010 |
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List of search results for chromosome breakage
