News tagged with chromosomal instability
Researchers identify potential cancer target
(PhysOrg.com) -- Dartmouth Medical School researchers have found two proteins that work in concert to ensure proper chromosome segregation during cell division. Their study is in the January 2009 issue of ...
Jan 16, 2009 |
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DNA replication protein Cdt1 also has a role in mitosis, cancer
The foundation of biological inheritance is DNA replication – a tightly coordinated process in which DNA is simultaneously copied at hundreds of thousands of different sites across the genome. If that ...
May 13, 2012 |
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A needle in a haystack: How does a broken DNA molecule get repaired?
Scientists from the Kavli Institute of Nanoscience at Delft University of Technology have discovered a key element in the mechanism of DNA repair. When the DNA double helix breaks, the broken end goes searching for the similar ...
May 03, 2012 |
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Simple fungus gives researchers new insight on key DNA process
(Phys.org) -- In the University of Oregon lab of Eric U. Selker, a simple fungus continues to provide big clues about a fundamental biological process that is essential for normal growth and development in ...
Apr 23, 2012 |
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Stress-induced genomic instability facilitates rapid cellular adaption in yeast
Cells trying to keep pace with constantly changing environmental conditions need to strike a fine balance between maintaining their genomic integrity and allowing enough genetic flexibility to adapt to inhospitable conditions. ...
Jan 29, 2012 |
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New light shed on chromosome fragility
Why are certain chromosome regions prone to breakages? The answer is crucial, as this fragility is involved in the development of tumors. A team from the Institut de Génétique et de Biologie Moleculaire et Cellulaire ...
Dec 26, 2011 |
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Chromosomal 'breakpoints' linked to canine cancer
North Carolina State University researchers have uncovered evidence that evolutionary "breakpoints" on canine chromosomes are also associated with canine cancer. Mapping these "fragile" regions in dogs may also have implications ...
Nov 03, 2011 |
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Degrading proteins to divide cells
A group of scientists led by the IRB Barcelona, Spain, researcher Ferran Azoran has identified the main instrument that Drosophila cells use to define the identity and function of the centromere in the Drosophila. A ...
Aug 26, 2011 |
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Researchers reveal a new mechanism of genomic instability
Researchers at NYU School of Medicine have discovered the cellular mechanisms that normally generate chromosomal breaks in bacteria such as E. coli. The study's findings are published in the August 18 issue of the journal ...
Aug 18, 2011 |
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Ends of chromosomes protected by stacked, coiled DNA caps, study finds
(PhysOrg.com) -- Researchers at the University of Pennsylvania School of Medicine are delving into the details of the complex structure at the ends of chromosomes. Recent work, e-published in Nature Structural & ...
Apr 20, 2011 |
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Exercise may prevent stress on telomeres, a measure of cell health
UCSF scientists are reporting several studies showing that psychological stress leads to shorter telomeres – the protective caps on the ends of chromosomes that are a measure of cell age and, thus, health. The findings ...
Medicine & Health / Medical research
Apr 04, 2011 |
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List of search results for chromosomal instability
