Receptor proteins could hold clues to antibiotic resistance in MRSA
Scientists at Imperial College London have identified four new proteins that act as receptors for an essential signalling molecule in bacteria such as MRSA.
Scientists at Imperial College London have identified four new proteins that act as receptors for an essential signalling molecule in bacteria such as MRSA.
For more than fifty years, researchers have been studying exactly how aspirin affects the human body. Despite thousands of publications on the topic, our understanding is still incomplete.
Professor of Biochemistry Emad Tajkhorshid and colleagues have discovered that membrane transporters help not just sugars and other specific substrates cross from one side of a cellular membrane to the other—water ...
RNA, once considered a bit player in the grand scheme by which genes encode protein, is increasingly seen to have a major role in human genetics. In a study presented in the April 25 issue of the journal Cell, researchers from T ...
Many proteins undergo extensive modification after being synthesized, particularly those that are secreted or embedded in the cell membrane. This is achieved within the Golgi apparatus (see image), a cellular ...
A three-dimensional image of one of the proteins that serves as an on-off switch as it binds to receptors on the surface of a cell suggests there may be a sort of main power switch that could be tripped. These surface receptors ...
(Phys.org) —In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of ...
(Phys.org) —Scientists at the U.S. Department of Energy's Argonne National Laboratory, in collaboration with researchers from the Sanford-Burnham Medical Research Institute in Orlando, Fla., recently determined ...
System-wide networks of proteins are indispensable for organisms. Function and evolution of these networks are among the most fascinating research questions in biology. Bioinformatician Thomas Rattei, University ...
Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...
(Phys.org) —BBSRC-funded researchers have developed a new strategy that can give scientists a better insight into how complex molecular machineries function in living cells.
What can green algae do for science if they weren't, well, green? That's the question biologists at UC San Diego sought to answer when they engineered a green alga used commonly in laboratories, Chlamydomonas reinhardtii, into a ...
Four billion years ago, soon after the planet cooled enough for life to begin, primordial cells may have replicated and divided without protein machinery or cell walls, relying instead on just a flimsy lipid membrane. New ...
(Phys.org)—While studying a mutant strain of yeast, Purdue University researchers may have found a new target for drugs to combat cholesterol and fungal diseases.
Scientists at the Center for Molecular Biology of Heidelberg University have gained new insight into the process of mitosis in mammalian cells. Researchers under the direction of Prof. Dr. Frauke Melchior, ...