News tagged with cellular proliferation
Scientists elevate little-studied cellular mechanism to potential drug target
For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes ...
Dec 11, 2011 |
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Scientists identify molecular basis for DNA breakage
Scientists from the Hebrew University have identified the molecular basis for DNA breakage, a hallmark of cancer cells. The findings of this research have just been published in the journal Molecular Cell.
Jul 19, 2011 |
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Chemotherapy resistance: A new lead?
UA62784: that is the name of a molecule capable of preventing the proliferation of cancerous cells in vitro, and thus causing their cellular death. Its effects appear to amplify that of other anticancer agents ...
May 31, 2011 |
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Suggesting genes' friends, Facebook-style
Scientists at the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Centre (DKFZ), both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes. ...
Mar 07, 2011 |
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Apoptotic mechanisms of octreotide on HepG2
A research team from Greece examined the effect of octreotide on cellular proliferation, apoptosis and caspase activation in HepG2 hepatocellular carcinoma (HCC) cells. The results supported the induction of caspase-mediated ...
Jan 31, 2011 |
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Novel protein critical for cellular proliferation discovered
Accurate duplication of genetic material and the faithful segregation of chromosomes are critical for cell survival. The initiation of DNA replication is linked both to cell cycle progression and chromatin organization. In ...
Oct 07, 2010 |
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Identification of a novel tumor suppressor
(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI), have identified a novel tumor suppressor playing an important role in T-cell lymphoma. The protein kinase NDR1 ...
Jun 21, 2010 |
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Newly discovered kinase regulates cytoskeleton, and perhaps holds key to how cancer cells spread
Scientists at the University of California, San Diego have identified a previously unknown kinase that regulates cell proliferation, shape and migration, and may play a major role in the progression or metastasis of cancer ...
May 31, 2010 |
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Research pinpoints action of protein linked to key molecular switch
Rho proteins have been described as "molecular switches" and play a role in cell migration, cell proliferation, cell death, gene expression, and multiple other common cellular functions.
Apr 19, 2010 |
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Disabling Skp2 gene helps shut down cancer growth
Increased understanding of the Skp2 gene and its relation to cellular senescence may lead to the development of novel agents that can suppress tumor development in common types of cancer, researchers from The University of ...
Medicine & Health / Medical research
Mar 17, 2010 |
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Enhancing arrest of cell growth to treat cancer in mice
A team of researchers, led by Pier Paolo Pandolfi, at Beth Israel Deaconess Medical Center, Boston, has identified a new type of cellular senescence (i.e., irreversible arrest of cell growth) and determined a way to enhance ...
Feb 08, 2010 |
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Possible pharmacological target(s) identified in pediatric OSA
Children with obstructive sleep apnea (OSA) may one day be able to have an injection or use a throat spray instead of getting their tonsils removed to cure their snoring, according to a new study from the University of Chicago, ...
Medicine & Health / Diseases, Conditions, Syndromes
Feb 04, 2010 |
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Heparanase-specific shRNA: A novel therapeutic strategy in human gastric cancer
Previous studies have indicated that the heparanase (HPA) is correlated with histopathological parameters and poor prognosis of gastric cancers. Although their efficiencies in inhibiting the expression of HPA, the traditional ...
Nov 25, 2009 |
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Messenger RNA with FLASH
A study from the University of North Carolina at Chapel Hill has identified a key player in a molecular process essential for DNA replication within cells.
Oct 22, 2009 |
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KEAP1 Keeps major cancer-promoting protein at bay
A tumor-suppressing protein snatches up an important cancer-promoting enzyme and tags it with molecules that condemn it to destruction, a research team led by scientists at The University of Texas M. D. Anderson ...
Oct 09, 2009 |
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