CRISPR-based tool maps gene function in human cells

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.

New technique switches key biomolecules on and off

A new technique that will allow scientists to determine the effects of turning on and off a set of molecules involved in almost every cellular pathway, determine their downstream effects, and uncover new drug targets has ...

Old Cells Work Differently

The agglutination and accumulation of proteins in nerve cells are major hallmarks of age-related neurodegenerative illnesses such as Alzheimer's disease. Cellular survival thus depends on a controlled removal of excessive ...

Gene network illuminates stress, mutation and adaptation responses

For much of her professional life, Dr. Susan Rosenberg has studied the puzzling response of bacteria to stress and the mutations that result. In the current issue of the journal Science, she puts together the pieces of that ...

Study uncovers key mechanisms of cell communication

(PhysOrg.com) -- A unique bridging process may be behind a mystery of intracellular communication, according to new Cornell research published Feb. 4 in the journal Cell.

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