Feedback loop maintains basal cell population

Notch – the protein that can help determine cell fate – maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein – TGF beta (transforming growth factor ...

Scientists develop new techniques to track how cells develop

Understanding how various cell types differentiate themselves during development is one of the fundamental questions in developmental biology. Using genome-editing tools, Harvard scientists are getting closer to finding answers.

Researchers uncover new function for cell master regulator

(PhysOrg.com) -- TORC1 is a master regulator in cells, playing a key role in such diverse processes as gene expression and protein synthesis. While previous studies have described the role that TORC1 plays in these processes, ...

Gene movements observed in vivo

Certain parts of DNA are highly mobile and their dynamic motion participates in controlling gene expression. The research team working under Maria-Elena Torres-Padilla, an Inserm research director at the Institute of Genetics ...

Widespread misinterpretation of gene expression data

Reproducibility is a major challenge in experimental biology, and with the increasing complexity of data generated by genomic-scale techniques this concern is immensely amplified. RNA-seq, one of the most widely used methods ...

Planting a new perspective on climate research

(Phys.org) —A study on the mechanisms of how plants respond and adapt to elevated levels of carbon dioxide (CO2) and higher temperatures has opened a new perspective in climate research. Lead researcher Qiong A. Liu (Alison) ...

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