Shedding light on health and zombie cells in aging

With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules. When a person is young, the immune system responds and eliminates senescent cells, ...

Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

What can worms tell us about human aging?

What can worms tell us about human ageing? A lot more than you'd think; as research led by the Babraham Institute but involving researchers from multiple disciplines drawn together from across the world has shown. In a cluster ...

Researchers uncover intracellular longevity pathway

The search for clues on how to live healthier, longer lives has led researchers at Baylor College of Medicine to look inside the cells of the worm Caenorhabditis elegans. The researchers report in the journal Developmental ...

How chromosome ends influence cellular aging

By studying processes that occur at the ends of chromosomes, a team of Heidelberg researchers has unravelled an important mechanism towards a better understanding of cellular aging. The scientists focused on the length of ...

The 'weakest link' in the aging proteome

Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are ...

Recycling fat might help worms live longer

Aging is generally accepted as a universal fact of life, but how do humans and other organisms age at the molecular level? At Sanford-Burnham Medical Research Institute (Sanford-Burnham), a team led by Malene Hansen, Ph.D., ...

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