The 'weakest link' in the aging proteome

Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are ...

Recycling fat might help worms live longer

Aging is generally accepted as a universal fact of life, but how do humans and other organisms age at the molecular level? At Sanford-Burnham Medical Research Institute (Sanford-Burnham), a team led by Malene Hansen, Ph.D., ...

How chromosome ends influence cellular aging

By studying processes that occur at the ends of chromosomes, a team of Heidelberg researchers has unravelled an important mechanism towards a better understanding of cellular aging. The scientists focused on the length of ...

Cellular metabolism self-adapts to protect against free radicals

Oxygen-consuming organisms obtain energy through cellular respiration, which is the transformation of carbohydrates and oxygen into carbon dioxide and water. This process also produces toxic oxygen radicals which must be ...

What can worms tell us about human aging?

What can worms tell us about human ageing? A lot more than you'd think; as research led by the Babraham Institute but involving researchers from multiple disciplines drawn together from across the world has shown. In a cluster ...

Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

page 1 from 2