Marine sponge chemical and synthetic derivatives hijack human enzyme to kill cells
A human enzyme converts chemicals produced by marine sponges and related synthetic derivatives into cell-killing compounds, shows a study published today in eLife.
A human enzyme converts chemicals produced by marine sponges and related synthetic derivatives into cell-killing compounds, shows a study published today in eLife.
Cell & Microbiology
May 11, 2022
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24
In a structural analysis that could help inform efforts to develop new drugs for treating a myriad of diseases, RIKEN biologists have shed light on how the interaction between key signaling proteins and their regulatory partners ...
Cell & Microbiology
Mar 15, 2022
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37
For cells to thrive, a complex network of three-dimensional structures assembles to read, copy and produce the genetic materials (DNA) needed for cellular function. Understanding how these structures form, and what happens ...
Cell & Microbiology
Mar 10, 2022
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110
Male and female mouse brains differ in important ways, according to a new study led by Stanford Medicine investigators.
Plants & Animals
Jan 21, 2022
10
298
Temperature and dissolved oxygen (DO) can affect a series of physiological and biochemical responses and drive the expression of regulatory genes. When water temperature increases, the solubility of oxygen decreases, leading ...
Plants & Animals
Jan 21, 2022
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18
WEHI researchers have produced the first molecular images of an enzyme that controls proteins to signal and communicate with each other in human cells. The discovery could help to solve the mystery cause of a rare group of ...
Cell & Microbiology
Jan 10, 2022
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96
Viral pathogens like the SARS-CoV-2 coronavirus change the interior structure of the cells they infect. These changes occur at the level of individual cell components—the organelles—and can provide information on how ...
Molecular & Computational biology
Dec 6, 2021
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216
Life-threatening bacteria are becoming ever more resistant to antibiotics, making the search for alternatives to antibiotics an increasingly urgent challenge. For certain applications, one alternative may be a special type ...
Biotechnology
Nov 23, 2021
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529
Sugars found on the surface of human cells influence COVID-19 infection, according to a University of Alberta-led study that is one of the first to observe this relationship and suggests that cells in the brain might be particularly ...
Biochemistry
Nov 11, 2021
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267
Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole ...
Molecular & Computational biology
Nov 1, 2021
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54