A group of researchers developed a promising fix to CRISPR-Cas9's problem with unwanted genetic changes using a method that allows them to turn off gene-editing until it reaches key cell cycle phases where more accurate repairs ...
Biotechnology
Dec 4, 2020
0
175
A team led by LMU's Veit Hornung has shown that a protein found in skin cells recognizes a specific nucleic acid intermediate that is formed during virus replication. This recognition process subsequently induces a potent ...
Cell & Microbiology
Nov 27, 2020
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49
As the global coronavirus pandemic continues, scientists are not only trying to find vaccines and drugs to combat it, but also to continuously learn more about the virus itself. "By now we can expect the coronavirus to become ...
Cell & Microbiology
Nov 23, 2020
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196
Organelles within cells are tiny engines encapsulating processes that allow the cells to live.
Biochemistry
Nov 13, 2020
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83
Researchers from UCPH have discovered how a mysterious function of the so called minichromosome maintenance (MCM) proteins protect the human cells against DNA instability, which can cause devastating diseases including cancer. ...
Cell & Microbiology
Oct 22, 2020
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136
Loading of replicative helicases onto DNA is a key event during the initiation of chromosomal DNA replication. It takes place at specific chromosomal regions termed origins and is facilitated by the ORC protein complex. By ...
Molecular & Computational biology
Sep 21, 2020
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74
Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against ...
Cell & Microbiology
Sep 14, 2020
0
112
Many viruses, including HIV and influenza A, mutate so quickly that identifying effective vaccines or treatments is like trying to hit a moving target. A better understanding of viral propagation and evolution in single cells ...
Biochemistry
Aug 20, 2020
0
175
In an unexpected new finding, biochemists at the University of Massachusetts Amherst report observing that a damage-containment system in stressed bacteria can become overrun and blocked, but that this leads to cells responding ...
Cell & Microbiology
Aug 6, 2020
0
75
A protein that is critical for retrovirus replication may select viral genetic material for packaging within the nuclei of host cells, rather than in the cytoplasm, as was previously believed. The research, led by a team ...
Cell & Microbiology
Jul 30, 2020
0
70
