Gene repression can be sex-specific

Researchers have shown for the first time that embryonic cells destined to become either egg or sperm rely on different methods of repressive gene regulation.

Researchers call for standards for biological imaging

Stained molecules in the cell nucleus, the inner life of a synaptic cleft, or the surface of a floral leaf: Modern microscopes enable researchers to examine processes that are otherwise invisible and located in tiniest structures ...

The vast little library inside your cells

The human genome can be thought of as a massive library, containing over 20,000 different "instruction manuals": your genes. For example, there are genes which contain information to build a brain cell, a skin cell, a white ...

Researchers film fundamental life process at cellular level

All proteins in a cell are assembled by complicated molecular machines. The precursors of these ribosomes are produced in the cell nucleus and then enter the cell through the so-called nuclear pores. Researchers at the University ...

New insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

Machine learning discovers new sequences to boost drug delivery

Duchenne muscular dystrophy (DMD), a rare genetic disease usually diagnosed in young boys, gradually weakens muscles across the body until the heart or lungs fail. Symptoms often show up by age 5; as the disease progresses, ...

Interior organization of the nucleolus discovered

The nucleolus—a conspicuous but obscure organelle within the cell nucleus—is normally too compact to be studied in detail. Researchers at Case Western Reserve University just learned how to simplify its structure in living ...

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