Lipid expansion microscopy uses 'power of click chemistry'

Lipids—fats—make great walls for cells and organelles because they are water resistant and dynamic. But those same characteristics also make them hard to image using expansion microscopy, a technique that works for magnifying ...

Researchers identify key player in cellular response to stress

An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests. The findings, published ...

Team investigates sex-determination mechanisms in birds

Scientists have known that sex-determination in vertebrates happens in the germ cells, a body's reproductive cells, and the somatic cells, the cells that are not reproductive cells. Yet they have not fully understood the ...

Bird neurons use three times less glucose than mammalian neurons

Birds have impressive cognitive abilities and show a high level of intelligence. Compared to mammals of about the same size, the brains of birds also contain many more neurons. Now a new study reported in Current Biology ...

Cross-species cell landscape constructed at single-cell level

Thanks to high-throughput single-cell RNA sequencing (scRNA-seq), it is possible to construct single-cell transcriptomic atlases at the organic level. For example, cell atlases for vertebrate and invertebrate systems have ...

First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

page 5 from 36