A team of researchers at Ehime University revealed that E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD. This finding was published on Sept. 20 in the Journal of Biological Chemistry.
Molecular & Computational biology
Oct 29, 2019
0
4
A hallmark of age-related diseases such as Parkinson's disease, type 2 diabetes, or Alzheimer's disease is the abnormal clumping of proteins in cells. In people with these conditions, these protein clumps can result in irregular ...
Biochemistry
Sep 16, 2019
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25
Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect. The ...
Cell & Microbiology
Aug 29, 2019
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452
In recent years, MIT scientists have developed a new model for how key genes are controlled that suggests the cellular machinery that transcribes DNA into RNA forms specialized droplets called condensates. These droplets ...
Biotechnology
Aug 8, 2019
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36
Why does it take 200 million sperm to fertilize a single egg?
Cell & Microbiology
Jul 18, 2019
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17
Ultrasound has long been an important tool for medical imaging. Recently, medical researchers have demonstrated that focused ultrasound waves can also improve the delivery of therapeutic agents such as drugs and genetic material. ...
Bio & Medicine
May 13, 2019
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22
Researchers from an international collaboration have succeeded in creating a "protein cage"—a nanoscale structure that could be used to deliver drugs to specific places of the body, and which can be readily assembled and ...
Materials Science
May 8, 2019
0
548
Engineered T cell immunotherapy, such as chimeric antigen receptor T cell (CAR-T) and T cell receptor T cell (TCR-T) therapy, has emerged as a potent therapeutic strategy for treating tumors.
Biochemistry
Apr 15, 2019
0
10
Fungal diseases collectively termed "powdery mildew" afflict a broad range of plant species, including agriculturally relevant cereals such as barley, and result in significant reductions in crop yield. Fungi that cause powdery ...
Plants & Animals
Feb 20, 2019
0
56
Researchers have developed a new AI-driven platform that can analyse how pathogens infect our cells with the precision of a trained biologist.
Cell & Microbiology
Feb 12, 2019
0
4
