Related topics: stem cells · transcription factors

Scientists discover a new mechanism to generate cartilage cells

As any weekend warrior understands, cartilage injuries to joints such as knees, shoulders, and hips can prove extremely painful and debilitating. In addition, conditions that cause cartilage degeneration, like arthritis and ...

Decoding mystery sequences involved in gene regulation

Every cell in an organism's body has the same copy of DNA, yet different cells do different things; for example, some function as brain cells, while others form muscle tissue. How can the same DNA make different things happen? ...

Researchers show stem cell fate depends on 'grip'

The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have ...

Neural stem cells control their own fate

To date, it has been assumed that the differentiation of stem cells depends on the environment they are embedded in. A research group at the University of Basel now describes for the first time a mechanism by which hippocampal ...

Research sheds light on M.O. of unusual RNA molecules

(Phys.org) —The genes that code for proteins—more than 20,000 in total—make up only about 1 percent of the complete human genome. That entire thing—not just the genes, but also genetic junk and all the rest—is coiled ...

Scientists find trigger to decode the genome

Scientists from The University of Manchester have identified an important trigger that dictates how cells change their identity and gain specialised functions.

Feedback loop maintains basal cell population

Notch – the protein that can help determine cell fate – maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein – TGF beta (transforming growth factor ...

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