Programmed cell death may be 1.8 billion years old

Apoptosis, often referred to as programmed cell death, is a fundamental process crucial to the growth and development of multicellular organisms. This process, or a primordial form of it, is also observed in single-celled ...

FRET-based biosensor visualizes execution of necroptosis in vivo

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points. For this ...

Understanding how autoactivation triggers cell death

Apoptosis is a process that causes cell death. It can go awry in cancer cells, sustaining the disease. Scientists at St. Jude Children's Research Hospital have captured the structure of BAK, a protein that triggers apoptosis. ...

Coronaviruses can induce host cell apoptosis

A large team of researchers working at the University of Hong Kong has found that three major types of coronaviruses are able to induce cell apoptosis in infected hosts. In their paper published in the journal Science Advances, ...

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