Numerous anti-cancer drugs function by targeting the DNA within cancerous cells, halting their proliferation. Yet, cancer cells occasionally develop mechanisms to repair the damage inflicted by these drugs, diminishing their ...
Molecular & Computational biology
Mar 12, 2024
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2
Over the past 30 years, Australia's Tasmanian devil population has been afflicted with an infectious cancer that has pushed the species to near extinction. The marsupials are highly susceptible to devil facial tumor disease, ...
Plants & Animals
Mar 12, 2024
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22
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs.
Biochemistry
Mar 7, 2024
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31
Researchers from the Bhogaraju Group at EMBL Grenoble have gained new insights into how a cancer-relevant family of proteins bind their targets. The results of the study, published in The EMBO Journal, could potentially help ...
Molecular & Computational biology
Mar 6, 2024
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0
Boston College researchers used a mild charge of electricity to precisely modify proteins, a new tool that can be used to develop novel biotherapeutics and protein-based research tools, the team reported recently in the journal ...
Biochemistry
Mar 5, 2024
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99
Vietnamese capital Hanoi was blanketed by a thick haze of pollution on Tuesday that obscured high-rise buildings and left the city's nearly nine million people breathing toxic air.
Environment
Mar 5, 2024
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9
Penn Engineers have developed a new means of targeting the lungs with lipid nanoparticles (LNPs), the minuscule capsules used by the Moderna and Pfizer-BioNTech COVID-19 vaccines to deliver mRNA, opening the door to novel ...
Bio & Medicine
Mar 1, 2024
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27
Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. In a study published ...
Bio & Medicine
Feb 28, 2024
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11
Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes. ...
Molecular & Computational biology
Feb 23, 2024
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18
Gene expression is controlled by numerous small RNA molecules called microRNAs, or miRNAs. However, specific functions of most miRNAs remain poorly understood. Working with worms, Friedrich Miescher Institute (FMI) researchers ...
Molecular & Computational biology
Feb 22, 2024
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