Iron nanorobots show their true mettle

Drug-coated iron nanowires that can be guided to the site of a tumor using an external magnetic field before activating a three-step cancer-killing mechanism could provide an effective option for cancer therapy.

Researchers reprogram T cells to improve cancer immunotherapy

St. Jude Children's Research Hospital scientists have identified a new therapeutic strategy that enhanced cancer immunotherapy, slowed tumor growth and extended the lives of mice with cancer. The research appears today in ...

Discovery of genes involved in the biosynthesis of antidepressant

St. John's Wort (Hypericum perforatum) is an ancient medicinal plant. It is known for the mild antidepressant properties of its bioactive compound hypericin, which is produced in the dark glands of the plant. By investigating ...

'Dual login' mechanism found to resist fungal infection in cells

Indiana University researchers have identified a mechanism involving the body's ability to resist fungal infection. The work could help advance research on cancer therapies that use the body's own immune system to fight disease.

New polymer releases molecular cargo in response to force

Caltech scientists have developed a new kind of polymer that can carry a chemical payload as part of its molecular structure and release it in response to mechanical stress. The chemical system they have developed could one ...

Completing DNA synthesis

The final stage of DNA replication—"termination"—occurs when two DNA copy machines advance upon each other and unwind the final stretch of DNA. This process occurs about 60,000 times per human cell cycle and is crucial ...

Cell stiffness may indicate whether tumors will invade

Engineers at MIT and elsewhere have tracked the evolution of individual cells within an initially benign tumor, showing how the physical properties of those cells drive the tumor to become invasive, or metastatic.

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