While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for mapping these structures in the genome. G4 CUT&Tag revealed numerous G4s in the human and ...
Biotechnology
Dec 6, 2021
0
52
DNA is the instruction manual for every living organism, guiding the development and functioning of all biological processes. In essence, it is a molecule with a double helix structure with each unit of a helix containing ...
Molecular & Computational biology
Sep 13, 2021
0
466
Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other ...
Biotechnology
Jul 6, 2021
0
18
Northwestern Medicine studies published in Nature Cell Biology and Molecular Cell are improving the understanding of epigenetic mechanisms in cancer development and progression, as well as pinpointing genes that drive the ...
Cell & Microbiology
May 6, 2021
0
28
Electrical engineers, computer scientists and biomedical engineers at the University of California, Irvine have created a new lab-on-a-chip that can help study tumor heterogeneity to reduce resistance to cancer therapies.
Bio & Medicine
Oct 7, 2020
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75
There is a broad range of mechanisms associated with chemoresistance, many of which to date are only poorly understood. The so-called cellular stress response—a set of genetic programs that enable the cells to survive under ...
Cell & Microbiology
Jun 10, 2020
0
141
San Francisco's women firefighters are exposed to higher levels of certain toxic PFAS chemicals than women working in downtown San Francisco offices, shows a new study led by researchers at the University of California, Berkeley, ...
Environment
Feb 26, 2020
0
14
The protein, called syndecan-4, combines with fellow cell membrane proteins, called integrins, to form protruding 'hands' that sense the environment outside the cell.
Biochemistry
Jan 6, 2020
0
27
George Mason University researchers have discovered the exact location where two proteins responsible for hiding cancer cells from the immune system bind. This discovery provides a novel approach to developing new cancer ...
Biochemistry
Oct 7, 2019
0
192
Many potential pharmaceuticals end up failing during clinical trials, but thanks to new research from the University of Illinois, biological molecules once considered for cancer treatment are now being repurposed as organic ...
Materials Science
Oct 2, 2019
0
252
