Women firefighters face high exposure to toxic PFAS chemicals

San Francisco's women firefighters are exposed to higher levels of certain toxic PFAS chemicals than women working in downtown San Francisco offices, shows a new study led by researchers at the University of California, Berkeley, ...

Enzyme 'atlas' helps researchers decipher cellular pathways

One of the most important classes of human enzymes are protein kinases—signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction in these cellular pathways ...

New cryo-EM images shed light on Wnt signaling

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported ...

Uncovering epigenetic mechanisms underlying cancer development

Northwestern Medicine studies published in Nature Cell Biology and Molecular Cell are improving the understanding of epigenetic mechanisms in cancer development and progression, as well as pinpointing genes that drive the ...

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