Numerous anti-cancer drugs function by targeting the DNA within cancerous cells, halting their proliferation. Yet, cancer cells occasionally develop mechanisms to repair the damage inflicted by these drugs, diminishing their ...
Molecular & Computational biology
Mar 12, 2024
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2
Researchers from the Bhogaraju Group at EMBL Grenoble have gained new insights into how a cancer-relevant family of proteins bind their targets. The results of the study, published in The EMBO Journal, could potentially help ...
Molecular & Computational biology
Mar 6, 2024
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0
Boston College researchers used a mild charge of electricity to precisely modify proteins, a new tool that can be used to develop novel biotherapeutics and protein-based research tools, the team reported recently in the journal ...
Biochemistry
Mar 5, 2024
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99
Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. In a study published ...
Bio & Medicine
Feb 28, 2024
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11
Gene expression is controlled by numerous small RNA molecules called microRNAs, or miRNAs. However, specific functions of most miRNAs remain poorly understood. Working with worms, Friedrich Miescher Institute (FMI) researchers ...
Molecular & Computational biology
Feb 22, 2024
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32
Cell therapies for cancer can be potentially enhanced using a CRISPR RNA-editing platform, according to a new study published Feb. 21 in Cell.
Cell & Microbiology
Feb 21, 2024
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70
Researchers at the Pritzker School of Molecular Engineering and the Department of Chemistry at the University of Chicago have engineered tiny, spinning micro-robots that bind to immune cells to probe their function. The robot, ...
Bio & Medicine
Feb 21, 2024
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6
Lung cancer is one of the most common cancers and has one of the lowest survival rates in the world. Cytokines, which are small signaling proteins, such as interleukin-12 (IL-12), have demonstrated considerable potential ...
Bio & Medicine
Feb 15, 2024
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122
The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts. Yet every cell in our bodies must have a way of differentiating ...
Cell & Microbiology
Feb 15, 2024
0
64
University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptides—molecules that hold promise in pharmaceuticals as they can bind to challenging ...
Biochemistry
Feb 14, 2024
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102
