Brain tumor cells decimated by mitochondrial 'smart bomb'
An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist ...
Gold nanotubes launch a three-pronged attack on cancer cells
Scientists have shown that gold nanotubes have many applications in fighting cancer: internal nanoprobes for high-resolution imaging; drug delivery vehicles; and agents for destroying cancer cells.
New nanoparticle gene therapy strategy effectively treats deadly brain cancer in rats
Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often ...
Buckyballs become bucky-bombs
In 1996, a trio of scientists won the Nobel Prize for Chemistry for their discovery of Buckminsterfullerene - soccer-ball-shaped spheres of 60 joined carbon atoms that exhibit special physical properties.
New nanodevice defeats drug resistance
Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking ...
Ultra-small block 'M' illustrates big ideas in drug delivery
By making what might be the world's smallest three-dimensional unofficial Block "M," University of Michigan researchers have demonstrated a nanoparticle manufacturing process capable of producing multilayered, precise shapes.
Team first to blend high-end imaging techniques
Vanderbilt University researchers have achieved the first "image fusion" of mass spectrometry and microscopy—a technical tour de force that could, among other things, dramatically improve the diagnosis ...
Fractal patterns may uncover new line of attack on cancer
Studying the intricate fractal patterns on the surface of cells could give researchers a new insight into the physical nature of cancer, and provide new ways of preventing the disease from developing.
How did multicellular life evolve?
Scientists are discovering ways in which single cells might have evolved traits that entrenched them into group behavior, paving the way for multicellular life. These discoveries could shed light on how complex ...
Unlikely pairing—an antidepressant plus dye—yields tumor-targeting tool
A team of scientists has created a "conjugate" molecule—one stitched together from two separate molecules—that seeks out and blocks prostate cancer growth in lab animals.
Magnetic material attracts attention for cancer therapy
An extraordinary self-regulating heating effect that can be achieved in a particular type of magnetic material may open the doors to a new strategy for hyperthermia cancer treatment.
Nano packages for anti-cancer drug delivery
Cancer stem cells are resistant to chemotherapy and consequently tend to remain in the body even after a course of treatment has finished, where they can often trigger cancer recurrence or metastasis. A new ...
Researchers discover genetic origins of myelodysplastic syndrome using stem cells
Induced pluripotent stem cells (iPSCs)—adult cells reprogrammed back to an embryonic stem cell-like state—may better model the genetic contributions to each patient's particular disease. In a process called cellular reprogramming, ...
Protein merlin regulates collective cell movement, promoting effective and rapid wound healing
Cells also follow a herd instinct, and they thereby communicate in a magical collective way. This is because a protein known as merlin, named after the mythical wizard of medieval England, plays an important ...