Calcium bursts kill drug-resistant tumor cells

Multidrug resistance (MDR)—a process in which tumors become resistant to multiple medicines—is the main cause of failure of cancer chemotherapy. Tumor cells often acquire MDR by boosting their production of proteins that ...

A calcium pump caught in the act

Researchers at Aarhus University have described one of the cell's key enzymes, the calcium pump, in its decisive moment—a so-called transition state. These findings provide a very detailed picture of how one of the most ...