News tagged with brca2
DNA and the 'magic rings' trick
(PhysOrg.com) -- A new study from UC Davis shows how, like a conjuring trick with interlocking rings, two interlocked pieces of DNA are separated after DNA is copied or repaired. The finding was published online Oct. 10 in ...
Oct 11, 2010 |
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Genetic 'hotspot' for breast cancer risk
Vanderbilt-Ingram Cancer Center investigators have identified a new genetic hotspot for breast cancer.
Feb 15, 2009 |
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Human DNA repair process recorded in action (Video)
(PhysOrg.com) -- A key phase in the repair process of damaged human DNA has been observed and visually recorded by a team of researchers at the University of California, Davis. The recordings provide new information ...
Biology /
Jan 29, 2009 |
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Protein made by breast cancer gene purified
A key step in understanding the origins of familial breast cancer has been made by two teams of scientists at the University of California, Davis. The researchers have purified, for the first time, the protein produced by ...
Aug 22, 2010 |
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Revolutionary therapy slows tumor growth in advanced breast cancer
The new drug olaparib has antitumour activity in carriers of the BRCA1 or BRCA2 gene mutations who have advanced ovarian or breast cancer, according to the findings of two proof-of-concept trials. Together with previous findings, ...
Jul 05, 2010 |
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Dartmouth researchers get personal with genetics
Two recent studies by Dartmouth researchers use individual genetic data to reveal the powers and limits of our current understanding of how the genome influences human health and what genes can reveal about the ancestry of ...
Sep 15, 2009 |
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First purification of cancer gene, BRCA2, studied by UNC scientists
Scientists at the University of North Carolina at Chapel Hill were among co-authors of a study that described the first isolation and purification of the BRCA2 protein which is produced by a gene whose loss ...
Sep 15, 2010 |
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Breast cancer patients with BRCA mutations 4 times more likely to get cancer in opposite breast
Women with breast cancer before age 55 who carry an inherited mutation in the breast cancer susceptibility genes BRCA1 or BRCA2 are four times more likely to develop cancer in the breast opposite, or contralateral, to their ...
Apr 05, 2010 |
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BRCA2 mutations associated with improved survival for ovarian cancer
Women with ovarian cancer who have the BRCA2 gene mutation are more likely to survive the malignancy than women with the BRCA1 mutation, or women without either mutation.
Apr 04, 2011 |
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Coping with genetic predisposition to cancer
Kelly Metcalfe, a professor at the Bloomberg Faculty of Nursing, focuses her research on a unique population of women faced with some really tough decisions and helps them reach satisfactory conclusions.
Sep 29, 2010 |
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New drug reduces tumor size in women with advanced hereditary ovarian or breast cancer
Understanding the underlying genetic weakness of certain types of cancer may lead to targeted therapy and provide the key to effective treatment, a new study suggests. An international consortium of researchers has shown ...
Aug 12, 2010 |
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Annual screening with breast ultrasound or MRI could benefit some women
Results of a large-scale clinical trial presented today at the annual meeting of the Radiological Society of North America (RSNA) provide the first strong evidence of the benefit of annual screening ultrasound for women with ...
Dec 02, 2009 |
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Gastroenterologists explore relationship between bacteria in the gut and breast cancer
The human body contains billions of microorganisms, and microbial cells found in the human gut are estimated to outnumber human cells by ten-to-one in healthy adults. However, little is known about the ways in which these ...
Oct 28, 2009 |
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Breast cancer: Risk increases for smokers and overweight women
A recent study published in the Journal of Cancer Epidemiology has reinforced the correlation between being overweight, smoking and breast cancer. What makes this study unique is how test subjects were not diagnosed for BR ...
Sep 01, 2009 |
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Genetic testing for breast or ovarian cancer risk may be greatly underutilized
Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with family histories of these ...
May 21, 2009 |
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BRCA2
More reference expression data
BRCA2 (Breast Cancer Type 2 susceptibility protein) is a protein that in humans is encoded by the BRCA2 gene. BRCA2 belongs to the tumor suppressor gene family and the protein encoded by this gene is involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double strand breaks.
The BRCA2 gene is located on the long (q) arm of chromosome 13 at position 12.3 (13q12.3), from base pair 31,787,616 to base pair 31,871,804.
For more information about BRCA2, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
