Unexpected insights into the dynamic structure of mitochondria

As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. Until now, it has been assumed that these functions underlie a static structure of mitochondrial membranes. ...

An easier way of sneaking antibodies into cells

For almost any conceivable protein, corresponding antibodies can be developed to block it from binding or changing shape, which ultimately prevents it from carrying out its normal function. As such, scientists have looked ...

Dynamic images show rhomboid protease in action

Rhomboid proteases are clinically relevant membrane proteins that play a key role in various diseases. Using solid-state NMR spectroscopy, researchers from Berlin's Leibniz-Forschungsinstitut für Molekulare Pharmakologie ...

Performing chemistry in floating droplets

Could chemists be ready to ditch the venerable test tube, the very symbol of chemistry in the minds of many people? Maybe not quite yet, but Caltech's Jack Beauchamp is working on it.

Sophisticated molecular machines in action

Almost all living organisms from bacteria to humans have gate-like protein complexes in their cell membranes that get rid of unwanted or life-threatening molecules. This is not always advantageous, since in the case of bacteria ...

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