Puzzling out the structure of a molecular giant

Combining AlphaFold2 with experimental and computational techniques has helped scientists figure out the human nuclear pore complex's architecture in greater detail than ever before.

New method melds data to make a 3-D map of cells' activities

Just as it's hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell's environment. To solve that problem, researchers ...

Finding additional ways that proteins rotate

Biological materials like bones, teeth, and seashells are impressively tough. This strength comes from their composition: a combination of hard rock-like minerals and resilient carbon-based molecules like proteins. Materials ...

Unprecedented videos show RNA switching 'on' and 'off'

Similar to a light switch, RNA switches (called riboswitches) determine which genes turn "on" and "off." Although this may seem like a simple process, the inner workings of these switches have confounded biologists for decades.

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