Related topics: protein

Watching a protein as it functions

(Phys.org) —When it comes to understanding how proteins perform their amazing cellular feats, it is often the case that the more one knows the less one realizes they know. For decades, biochemists and biophysicists have ...

Protein strongest just before death

(Phys.org)—Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave.

Biochemists trap a chaperone machine in action

Molecular chaperones have emerged as exciting new potential drug targets, because scientists want to learn how to stop cancer cells, for example, from using chaperones to enable their uncontrolled growth. Now a team of biochemists ...

Iron-sulfur enzymes as candidates for antibiotic development

The iron-sulfur protein IspH plays a central role in the terpene metabolism of several pathogens. The mechanism of the reaction provides an approach for developing new antibiotics, particularly against malaria and tuberculosis. ...

Making sense of misfolded proteins

The endoplasmic reticulum of cells provides a pivotal quality-control system that eliminates improperly folded, or misfolded, glycoproteins, such as antibodies and hormones. The UDP-glucose:glycoprotein glycotransferase (UGGT) ...

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