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Immunoproteasome crystal structure determined

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells ...

dateFeb 16, 2012 in Biochemistry
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Active compounds against Alzheimer's disease

More than half of all cases of dementia in the elderly can be attributed to Alzheimer's disease. Despite vast research efforts, an effective therapy has not been developed, and treatment consists of dealing with the symptoms. ...

dateJan 12, 2012 in Biochemistry
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Long-standing plant biochemistry mystery solved

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and collaborators at the Karolinska Institute in Sweden have discovered how an enzyme "knows" where to insert a double bond when desaturating ...

dateSep 19, 2011 in Biochemistry
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A chaperone for the 'guardian of the genome'

The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...

dateSep 07, 2011 in Biotechnology
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