News tagged with binding site

Related topics: antibodies

Scorpion venom with nanoparticles slows spread of brain cancer

By combining nanoparticles with a scorpion venom compound already being investigated for treating brain cancer, University of Washington researchers found they could cut the spread of cancerous cells by 98 ...

Nanotechnology / Bio & Medicine

created Apr 16, 2009 | popularity 4.6 / 5 (10) | comments 3

Team reveals all three structures of single transporter protein

A team of researchers from the Universities of Leeds, Oxford and Imperial College London have captured the 3D atomic models of a single transporter protein in each of its three main structural states, a goal ...

Biology / Cell & Microbiology

created Apr 22, 2010 | popularity 4.7 / 5 (6) | comments 0 | with audio podcast

Chemists discover how antiviral drugs bind to and block flu virus

Antiviral drugs block influenza A viruses from reproducing and spreading by attaching to a site within a proton channel necessary for the virus to infect healthy cells, according to a research project led ...

Chemistry / Biochemistry

created Feb 03, 2010 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Study finds a weak spot on deadly ebolavirus

Scientists from The Scripps Research Institute and the US Army's Medical Research Institute of Infectious Diseases have isolated and analyzed an antibody that neutralizes Sudan virus, a major species of ebolavirus ...

Biology / Cell & Microbiology

created Nov 21, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Can't live without it: The nicotine addiction

The first pull on a cigarette should send you into convulsions. The brain proteins that nicotine affects are nearly identical to a receptor protein on muscle cells that tells them to contract, but nicotine ...

Medicine & Health / Health

created Sep 23, 2010 | popularity 5 / 5 (3) | comments 0

Mirror images united: Simultaneous binding of both enantiomers of a drug to an enzyme

(PhysOrg.com) -- In the binding pockets of enzymes their natural binding partners fit exactly. The principle by which many pharmacological agents work also relies on the fact that these substances fit exactly into the pockets ...

Chemistry / Biochemistry

created Oct 29, 2009 | popularity 5 / 5 (2) | comments 0

Molecular simulations explain how enzymatic pumps transport calcium ions within muscle cells

The transport of ions is essential for the routine maintenance of the body. For this reason cells contain specialized enzymes that act as pumps that help ions to move around and pass through boundaries.

Biology / Cell & Microbiology

created Feb 18, 2011 | popularity 5 / 5 (2) | comments 3

Key enzyme discovered to be master regulator in protein-protein reactions

Protein phosphorylation is a process by which proteins are flipped from one activation state to another. It is a crucial function for most living beings, since phosphorylation controls nearly every cellular ...

Biology / Cell & Microbiology

created Mar 24, 2010 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Biologists reveal novel drug binding site in NMDA receptor subunit

Structural biologists at Cold Spring Harbor Laboratory (CSHL) have obtained a precise molecular map of the binding site for an allosteric inhibitor in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which is commonly ...

Biology / Cell & Microbiology

created Jun 16, 2011 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast