Molecular 'hub' regulates gene-silencing proteins

To keep their vital functions in balance, many organisms use small snippets of RNA to "silence" messenger RNAs that code for certain proteins. New research from FMI scientists has revealed a molecular hub that integrates ...

Cell cytoskeleton as target for new active agents

Through a unique combination of computer simulations and laboratory experiments, researchers at the Paul Scherrer Institute (PSI) have discovered new binding sites for active agents—against cancer, for example—on a vital ...

Searching the COVID-19 spike protein for a potential vaccine

The virus that causes COVID-19 is studded on its exterior with "spike proteins," a key component in its ability to infect human cells. Two University of Georgia researchers, Rob Woods and Parastoo Azadi, are investigating ...

Multiple modes for selectivity of transmembrane transport

LMU researchers utilized a biophysical approach to understand how bacterial import proteins bind and selectively convey their cargoes across membranes. The results reveal an unexpectedly wide variety of transfer mechanisms.

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