News tagged with beta amyloid
Modulating a protein in the brain could help control Alzheimer's disease
A protein known to exist in the brain for more than 30 years, called 5-lipoxygenase, has been found to play a regulatory role in the formation of the amyloid beta in the brain, the major component of plaques implicated in ...
Medicine & Health / Neuroscience
Nov 18, 2010 |
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Proteins linked to longevity also linked to Alzheimer's
Over the past 20 years, scientists have learned that proteins called sirtuins play a vital role in longevity and stress response in organisms as diverse as humans, yeast and mice. A new paper from MIT biologists ...
Medicine & Health / Medical research
Jul 27, 2010 |
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Studies demonstrate link among Alzheimer's disease, Down syndrome and atherosclerosis
Nearly 20 years ago Huntington Potter kicked up a storm of controversy with the idea that Down syndrome and Alzheimer's were the same disease. Now the evidence is in: He was right.
Medicine & Health / Medical research
Jan 16, 2010 |
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Delaying the aging process protects against Alzheimer's disease
Aging is the single greatest risk factor for Alzheimer's disease. In their latest study, researchers at the Salk Institute for Biological Studies found that simply slowing the aging process in mice prone to ...
Medicine & Health / Neuroscience
Dec 10, 2009 |
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Protein inhibitor helps rid brain of toxic tau protein
Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University ...
Medicine & Health / Neuroscience
Sep 29, 2009 |
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Alzheimer's research yields potential drug target
Scientists at UC Santa Barbara and several other institutions have found laboratory evidence that a cluster of peptides may be the toxic agent in Alzheimer's disease. Scientists say the discovery may lead ...
Jul 01, 2009 |
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Variant form of amyloid beta hinders amyloidogenesis, development of Alzheimer's disease
Alzheimer's disease causes misfolding and aggregation of a protein fragment known as amyloid beta and its deposition as plaques in the brain. This process triggers a cascade of event that leads to neurodegeneration. A new ...
Medicine & Health / Neuroscience
Mar 12, 2009 |
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Forgotten and lost - when proteins 'shut down' our brain
(PhysOrg.com) -- Which modules of the tau protein, in neurons of Alzheimer disease patients, may act in a destructive manner were investigated by researchers from the Max Planck Institute for Biophysical Chemistry ...
Biology /
Feb 17, 2009 |
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Active compounds against Alzheimer's disease
More than half of all cases of dementia in the elderly can be attributed to Alzheimer's disease. Despite vast research efforts, an effective therapy has not been developed, and treatment consists of dealing with the symptoms. ...
Jan 12, 2012 |
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Asthma drug could help control or treat Alzheimer's disease
A drug used to treat asthma has been shown to help reduce the formation of amyloid beta, a peptide in the brain that is implicated in the development of Alzheimer's disease, according to researchers at Temple University's ...
Medicine & Health / Medical research
Mar 25, 2011 |
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Study of cerebrospinal fluid reveals potential new Alzheimer's gene
A genomic study of cerebrospinal fluid (CSF) has added a new gene to the list of potential genetic contributors to Alzheimer's disease, a national research team led by Indiana University School of Medicine ...
Medicine & Health / Neuroscience
Dec 14, 2010 |
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Researchers find dementia in diabetics differs from dementia in nondiabetics
Researchers from Mayo Clinic's Florida campus say that dementia in some diabetics appears to be caused often by vascular disease in the brain, and the dementia that develops in people without diabetes is more likely associated ...
Medicine & Health / Diseases, Conditions, Syndromes
Jul 14, 2010 |
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Extended youthfulness as a prevention for Alzheimer's disease
Therapies that can keep us younger longer might also push back the clock on Alzheimer's disease, suggests a new study of mice in the December 11th issue of the journal Cell, a Cell Press publication.
Medicine & Health / Medical research
Dec 10, 2009 |
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Metal Deficit in Mouse Brain Plaques Guides Direction of Human Alzheimer's Disease Research
(PhysOrg.com) -- Minuscule plaques in the brains of mice with Alzheimer's disease contain much less metal than the brains of affected humans, according to a study conducted at the NSLS. This surprising finding ...
Medicine & Health / Neuroscience
Nov 04, 2009 |
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Oxygen treatment hastens memory loss in Alzheimer's mice
A 65-year-old women goes into the hospital for routine hip surgery. Six months later, she develops memory loss and is later diagnosed with Alzheimer's Disease. Just a coincidence? Researchers at the University of South ...
Medicine & Health / Neuroscience
Aug 11, 2009 |
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Beta amyloid
Amyloid beta (Aβ or Abeta) is a peptide of 39–43 amino acids that appear to be the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis, a muscle disease. Aβ also forms aggregates coating cerebral blood vessels in cerebral amyloid angiopathy. These plaques are composed of a tangle of regularly ordered fibrillar aggregates called amyloid fibers, a protein fold shared by other peptides such as prions associated with protein misfolding diseases. Research on laboratory rats suggest that the two-molecule, soluble form of the peptide is a causative agent in the development of Alzheimer's and that the two-molecule form is the smallest synaptotoxic species of soluble amyloid beta oligomer
For more information about Beta amyloid, read the full article at
Wikipedia.
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