Scientists have revealed how a bacterial enzyme has evolved an energy-efficient method to move long distances along DNA. The findings, published in Science, present further insight into the coupling of chemical and mechan ...
Apr 19, 2013
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(Phys.org) —In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of ...
Apr 09, 2013
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(Phys.org)—Worldwide, many strains of the bacterium Staphyloccocus aureus, commonly known as staph infections, are already resistant to all antibiotics except vancomycin. But as bacteria are becoming resistant to this o ...
Jan 30, 2013
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Crafting high-quality artisanal cheese is not complicated, but it's also not easy. Basically, heat a lot of milk, add bacterial cultures and enzymes to thicken it into a curd, drain it, salt it, and let it ferment and age. ...
Dec 17, 2012
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A new study by researchers at Imperial College London has identified a way in which Salmonella bacteria, which cause gastroenteritis and typhoid fever, counteract the defence mechanisms of human cells.
Nov 15, 2012
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(Phys.org)—What if you could take greenhouse gas and convert it to fuel for an energy-hungry world?
Nov 13, 2012
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One can often begin to understand a protein's function by identifying its accomplices in the cell. Accordingly, scientists have developed diverse biochemical assays that essentially allow them to go 'fishing' ...
Oct 10, 2012
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Next week's Journal of Biological Chemistry "Paper of the Week" by Wai Mun Huang and colleagues at the University of Utah Health Sciences Center and the University of Minnesota reveals new insights into the molecular proper ...
Jul 11, 2012
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(Phys.org) -- Genetic engineers and genomics researchers should welcome the news from the Lawrence Berkeley National Laboratory (Berkeley Lab) where an international team of scientists has discovered a new ...
Jun 28, 2012
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Researchers at the RIKEN SPring-8 Center in Harima, Japan, have clarified the crystal structure of quinol dependent nitric oxide reductase (qNOR), a bacterial enzyme that offers clues on the origins of our ...
Jan 22, 2012
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(PhysOrg.com) -- Colorado State University researchers have discovered an enzyme that is critical to the survival and replication of the bacterial pathogen that causes tuberculosis. The enzyme may become a key target for ...
Nov 21, 2011
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(PhysOrg.com) -- University of Waikato researchers have managed to create a billion-year-old bacterial enzyme and then trace its evolution through history, to the modern day.
Nov 01, 2011
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A recent study into the interactions between aminoglycoside antibiotics and their target site in bacteria used computer simulations to elucidate this mechanism and thereby suggest drug modifications.
Jul 21, 2011
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Slight oscillations lasting just milliseconds have a huge impact on an enzyme's function, according to a new study by Scripps Research Institute scientists. Blocking these movements, without changing the enzyme's overall ...
Apr 07, 2011
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A key enzyme in Mycobacterium tuberculosis that enables the microbe to reproduce rapidly could be a golden target for new drugs against tuberculosis (TB), according to a study published in Microbiology on 17 November. ...
Nov 17, 2010
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