Related topics: autoimmune diseases

Immunoproteasome crystal structure determined

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells ...

One lock, many keys

German researchers discover how immune system B-cells can react to very different substances.

Researchers identify 2 key pathways in adaptive response

UCSF researchers have identified the two key circuits that control a cell's ability to adapt to changes in its environment, a finding that could have applications ranging from diabetes and autoimmune research to targeted ...

Understanding a target of quinoline drugs

The full details about the molecules and mechanisms that underlie the development of autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, remain to be discovered. One compound that may have a ...

Two distinct molecular pathways can make regulatory immune cells

Finding a way to bypass the molecular events involved in autoimmunity - where the body's immune system mounts a self-directed attack - could lead to new treatments for autoimmune disorders and chronic infections. A study ...

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