New 'decision aid' for CRISPR immune responses

Friend or foe? Immune systems constantly face this question. They must recognize and clear foreign invaders without eliciting autoimmunity. Prokaryotic CRISPR-Cas systems recognize invaders based on genetic sequence. But ...

A single protein regulates 2 immune pathways

Unchecked, the natural or innate immune system can run out of control - like a stuck accelerator on a car. Eventually, it will kill the host it is supposed to protect.

Free web service for deep study of cell functions

A group of scientists from Russia, the U.S., Canada and Germany has developed a simple and effective web service called Genes And Metabolites (GAM) to help researchers study complex biological processes in cells. The program ...

Understanding a target of quinoline drugs

The full details about the molecules and mechanisms that underlie the development of autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, remain to be discovered. One compound that may have a ...

Research reveals how key controller protein is switched on

New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated. The discovery answers a key question about one of the most widely-researched proteins ...

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