News tagged with atm mutations

Tumor mutations can predict chemo success

(PhysOrg.com) -- New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy.

Medicine & Health / Cancer

created Aug 06, 2009 | popularity not rated yet | comments 2




Search results for atm mutations


Tumors resistant to radiation therapy may be controlled by the MET oncogene

Ionizing radiation treats many cancers effectively, but in some patients a few tumor cells become resistant to radiation and go on to cause relapse and metastasis. A growth factor-receptor protein called MET may be a key ...

Medicine & Health / Cancer

created Apr 04, 2011 | popularity not rated yet | comments 0

The past, present and future of cancer

Leading cancer researchers reflected on past achievements and prospects for the future of cancer treatment during a special MIT symposium on Wednesday titled “Conquering Cancer through the Convergence of Science and ...

Medicine & Health / Cancer

created Mar 18, 2011 | popularity not rated yet | comments 0

Cancer-causing virus exploits key cell-survival proteins

A cancer-causing retrovirus exploits key proteins in its host cells to extend the life of those cells, thereby prolonging its own survival and ability to spread, according to a new study by researchers at The Ohio State University ...

Chemistry / Biochemistry

created Feb 22, 2011 | popularity 4 / 5 (1) | comments 0

A better way to target tumors

In the past 40 years, scientists have learned a great deal about how cells become cancerous. Some of that knowledge has translated to new treatments, but most of the time doctors are forced to rely on standard ch ...

Medicine & Health / Cancer

created Nov 15, 2010 | popularity 5 / 5 (1) | comments 0

Blocking DNA repair protein could lead to targeted, safer cancer therapy

Researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have discovered that inhibiting a key molecule in a DNA repair pathway could provide the means to make cancer cells more sensitive ...

Medicine & Health / Cancer

created Jun 01, 2010 | popularity 5 / 5 (2) | comments 0

Rare ATM gene mutations, plus radiation, may increase risk of a second breast cancer

Certain rare mutations in the ataxia telangiectasia mutated (ATM) gene, combined with radiation exposure, may increase a woman's risk of developing a second cancer in the opposite breast, according to a study published online ...

Medicine & Health / Cancer

created Mar 19, 2010 | popularity not rated yet | comments 0

Researchers discover second protective role for tumor-suppressor

ATM, a protein that reacts to DNA damage by ordering repairs or the suicide of the defective cell, plays a similar, previously unknown role in response to oxidative damage outside of the nucleus, researchers report this week ...

Medicine & Health / Cancer

created Feb 18, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Biologists develop efficient genetic modification of human embryonic stem cells

Biologists have developed an efficient way to genetically modify human embryonic stem cells. Their approach, which uses bacterial artificial chromosomes to swap in defective copies of genes, will make possible the rapid development ...

Biology / Cell & Microbiology

created Jan 07, 2010 | popularity 5 / 5 (1) | comments 0

Study identifies two chemicals that could lead to new drugs for genetic disorders

UCLA scientists have identified two chemicals that convince cells to ignore premature signals to stop producing important proteins. Published in the Sept. 28 edition of the Journal of Experimental Medicine, the findings could ...

Medicine & Health / Medical research

created Sep 28, 2009 | popularity 5 / 5 (1) | comments 0

Stress makes your hair go gray

Those pesky graying hairs that tend to crop up with age really are signs of stress, reveals a new report in the June 12 issue of Cell.

Biology / Cell & Microbiology

created Jun 11, 2009 | popularity 4 / 5 (11) | comments 3


List of search results for atm mutations