News tagged with ataxia telangiectasia like disease
Study shows how defective DNA repair triggers 2 neurological diseases
Scientists at St. Jude Children's Research Hospital have teased apart the biological details distinguishing two related neurological diseases—ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS).
Jan 15, 2009 |
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Researchers pinpoint how one cancer gene functions
For several decades, researchers have been linking genetic mutations to diseases ranging from cancer to developmental abnormalities. What hasn't been clear, however, is how the body's genome sustains such destructive glitches ...
Feb 02, 2011 |
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Blocking DNA repair protein could lead to targeted, safer cancer therapy
Researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have discovered that inhibiting a key molecule in a DNA repair pathway could provide the means to make cancer cells more sensitive ...
Jun 01, 2010 |
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Biologists develop efficient genetic modification of human embryonic stem cells
Biologists have developed an efficient way to genetically modify human embryonic stem cells. Their approach, which uses bacterial artificial chromosomes to swap in defective copies of genes, will make possible the rapid development ...
Jan 07, 2010 |
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Study identifies two chemicals that could lead to new drugs for genetic disorders
UCLA scientists have identified two chemicals that convince cells to ignore premature signals to stop producing important proteins. Published in the Sept. 28 edition of the Journal of Experimental Medicine, the findings could ...
Medicine & Health / Medical research
Sep 28, 2009 |
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Protein's essential role in repairing damaged cells revealed
University of Michigan researchers have discovered that a key protein in cells plays a critical role in not one, but two processes affecting the development of cancer.
Biology /
Jan 06, 2009 |
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Breakthrough in cell-type analysis offers new ways to study development and disease
(PhysOrg.com) -- Like skilled assassins, many diseases seem to know exactly what types of cells to attack. While decimating one cadre of cells, diseases will inexplicably spare a seemingly identical group ...
Biology /
Nov 14, 2008 |
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Breakthrough in cell-type analysis offers new ways to study development and disease
Like skilled assassins, many diseases seem to know exactly what types of cells to attack. While decimating one cadre of cells, diseases will inexplicably spare a seemingly identical group of neighbors. What makes cells vulnerable ...
Medicine & Health / Medical research
Nov 13, 2008 |
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Scientists find new genes linked to lung cancer
Working as part of a multi-institutional collaboration, scientists at Washington University School of Medicine in St. Louis have assembled the most complete catalog to date of the genetic changes underlying the most common ...
Oct 22, 2008 |
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First glimpse of a key DNA repair protein at work
Repairing breaks in the two strands of the DNA double helix is critical for avoiding cancer. In humans and other organisms, a molecular machine called the MRN complex is responsible for finding and signaling ...
Biology /
Oct 03, 2008 |
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Protein 'chatter' linked to cancer activation
Scientists have found the existence of cross-talk between human chromosome ends and the protein complexes central to the stability of the entire human genome, a “chat” that contributes to cancer development.
Aug 13, 2007 |
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