News tagged with antimalarials

Scientists characterize protein essential to survival of malaria parasite

A biology lab at Washington University has just cracked the structure and function of a protein that plays a key role in the life of a parasite that killed 655,000 people in 2010.

Chemistry / Biochemistry

created Jan 06, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists identify new class of antimalarial compounds

An international team led by scientists from the Genomics Institute of the Novartis Research Foundation (GNF) and The Scripps Research Institute has discovered a family of chemical compounds that could lead ...

Chemistry / Biochemistry

created Nov 17, 2011 | popularity 3 / 5 (2) | comments 2 | with audio podcast

Scientists find genetic basis for key parasite function in malaria

Snug inside a human red blood cell, the malaria parasite hides from the immune system and fuels its growth by digesting hemoglobin, the cell's main protein. The parasite, however, must obtain additional nutrients ...

Biology / Biotechnology

created May 26, 2011 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Newer antimalarials more effective than quinine against severe malaria

Quinine should no longer be the drug of choice for treating severe malaria, according to an updated systematic review by Cochrane researchers. It is now evident that the antimalarial drug artesunate, which is derived from ...

Medicine & Health / Diseases, Conditions, Syndromes

created Mar 16, 2011 | popularity not rated yet | comments 0

Most effective malaria drug regimens highlighted in study

A study published today identifies the most effective drug combinations recommended for use as first-line treatments for malaria. The research also suggests that augmenting the treatments with a single dose ...

Medicine & Health / Diseases, Conditions, Syndromes

created Sep 09, 2010 | popularity not rated yet | comments 0

Antimalarial drug artemisinin moves into production

(PhysOrg.com) -- A semi-synthetic version of the antimalarial drug artemisinin developed by UC Berkeley's Jay Keasling is moving out of development into full-scale production, helped along by a $10.7 million grant from the ...

Medicine & Health / Medications

created Jul 12, 2010 | popularity 5 / 5 (2) | comments 0

A new method for developing safer drugs

Amodiaquine was introduced as an antimalarial drug, but was withdrawn when serious adverse effects were observed. Scientists at the University of Gothenburg, Sweden, have now developed a method that can be used to develop ...

Medicine & Health / Medical research

created May 10, 2010 | popularity not rated yet | comments 0

Discovery provides new drug targets for malaria cure

Researchers are a step closer to developing new antimalarial drugs after discovering the normal function of a set of proteins related to the malaria parasite protein, which causes resistance to the front-line drug chloroquine. ...

Medicine & Health / Medical research

created Jan 11, 2010 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Up a little on the left... now, over to the right... Scientists find a source of nonallergic itch

Scratching below the surface of a troublesome sensation that's equal parts tingle-tickle-prickle, sensory scientists from Johns Hopkins have discovered in mice a molecular basis for nonallergic itch.

Medicine & Health / Medical research

created Dec 22, 2009 | popularity 4.8 / 5 (4) | comments 0

Continued vigilance against drug-resistance malaria is needed

Current combination malaria therapies recommended by the World Health Organisation (WHO) provide adequate treatment for mild malaria, according to a Cochrane Systematic Review of the evidence. However, selected trials had ...

Medicine & Health / Diseases, Conditions, Syndromes

created Jul 08, 2009 | popularity not rated yet | comments 0

Tryptophan deficiency may underlie quinine side effects

Researchers have found that the anti-malarial drug quinine can block a cell's ability to take up the essential amino acid tryptophan, a discovery that may explain many of the adverse side-effects associated ...

Chemistry / Biochemistry

created Jun 26, 2009 | popularity 4.8 / 5 (4) | comments 1