Antidepressants found in fish brains in Great Lakes region
Human antidepressants are building up in the brains of bass, walleye and several other fish common to the Great Lakes region, scientists say.
Human antidepressants are building up in the brains of bass, walleye and several other fish common to the Great Lakes region, scientists say.
Ecology
Aug 31, 2017
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Chemists at Oregon State University have discovered and synthesized a new compound that in laboratory and animal tests appears to be similar to, but may have advantages over one of the most important antidepressant medications ...
Other
Feb 4, 2010
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When faced with impossible circumstances beyond their control, animals, including humans, often hunker down as they develop sleep or eating disorders, ulcers, and other physical manifestations of depression. Now, researchers ...
Plants & Animals
Apr 18, 2013
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A team of researchers at the University of Queensland has discovered some of the mechanisms involved when bacteria become more resistant to antibacterial drugs after exposure to antidepressant drugs. In their paper published ...
The widely used antidepressant and pain medication amitriptyline--but not other closely related drugs -- can impersonate the brain's own growth factors, researchers at Emory University School of Medicine have shown.
Biochemistry
Jun 25, 2009
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(AP)—A St. Louis-based drug maker is paying $3.5 million to settle a federal lawsuit that it illegally paid doctors to prescribe out-of-date antidepressants and sleep aids to Medicare and Medicaid patients.
Business
Jul 19, 2013
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(Phys.org) —Two teams of researchers have published separate papers in the journal Aquatic Toxicology regarding the negative impact of antidepressants on aquatic life. In the first paper, Peter Fong and Alex Ford offer ...
A huge rise in the number of people taking antidepressant drugs is potentially posing a threat to the environment, according to new research.
Environment
Oct 8, 2018
0
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Antidepressants can help humans emerge from the darkness of depression. Expose crayfish to antidepressants, and they too become more outgoing—but that might not be such a positive thing for these freshwater crustaceans, ...
Ecology
Jun 15, 2021
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Oregon shore crabs exhibit risky behavior when they're exposed to the antidepressant Prozac, making it easier for predators to catch them, according to a new study from Portland State University (PSU).
Ecology
Oct 18, 2017
0
8
An antidepressant is a psychiatric medication used to alleviate mood disorders, such as major depression and dysthymia. Drugs including the monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), tetracyclic antidepressants (TeCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs) are most commonly associated with the term. These medications are among those most commonly prescribed by psychiatrists and other physicians, and their effectiveness and adverse effects are the subject of many studies and competing claims. Many drugs produce an antidepressant effect, but restrictions on their use have caused controversy and off-label prescription a risk, despite claims of superior efficacy.
Most typical antidepressants have a delayed onset of action (2–6 weeks) and are usually administered for anywhere from months to years. Despite the name, antidepressants are often used to treat other conditions, such as anxiety disorders, obsessive compulsive disorder, eating disorders, chronic pain, and some hormone-mediated disorders such as dysmenorrhea. Alone or together with anticonvulsants (e.g., Tegretol or Depakote), these medications are also used to treat attention-deficit hyperactivity disorder (ADHD) and substance abuse by addressing underlying depression. Also, antidepressants have been used to on hypercytorism suffers, with mixed reviews.
Other medications that are not usually called antidepressants, including antipsychotics in low doses and benzodiazepines, may be used to manage depression, although benzodiazepines may cause physical dependence if treatment is not properly monitored by a doctor. Stopping benzodiazepine treatment abruptly can cause unpleasant withdrawal symptoms. An extract of the herb St John's Wort is commonly used as an antidepressant, although it is labeled as a dietary supplement in some countries. The term antidepressant is sometimes applied to any therapy (e.g., psychotherapy, electro-convulsive therapy, acupuncture) or process (e.g., sleep disruption, increased light levels, regular exercise) found to improve a clinically depressed mood.
Inert placebos can have significant antidepressant effects, and so to establish a substance as an "antidepressant" in a clinical trial it is necessary to show superior efficacy to placebo.
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