Computer-aided systems may speed up new anticancer drug development
New drug discovery is a complicated, expensive and time-consuming process. Traditional drug development pipeline needs 12 years and $2.7 billion USD on average.
New drug discovery is a complicated, expensive and time-consuming process. Traditional drug development pipeline needs 12 years and $2.7 billion USD on average.
Molecular & Computational biology
Jul 31, 2020
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Medications are developed to work well for most people, but those whose genetic makeup causes them to metabolize medicine too quickly often need higher doses of the drugs they take in order for them to be effective. For others, ...
Biochemistry
May 27, 2020
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106
The calcium mineral from which many shellfish, such as cockles, make their shells can be used to form nanoparticles. These nanoparticles can then be "loaded" with small drug molecules, such as anticancer drugs.
Bio & Medicine
May 22, 2020
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Three functional molecules (near-infrared fluorescent probe, tumor targeting molecule, and an anticancer drug) are successfully decollated onto the surface of a graphene molecule. This multi-functional graphene allows effective ...
Bio & Medicine
Apr 23, 2020
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Using "Trojan horses" to combat cancer from within the tumour cells themselves without damaging healthy tissues is the aim of this new tool created by researchers from the University of Granada (UGR), the Institute of Nanoscience ...
Materials Science
Nov 19, 2019
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22
The biological technique of 'optogenetics' uses light to control cells within living tissues that have been genetically modified to be light-sensitive. However, there is limited control of processes like this, as the light ...
Nanomaterials
Oct 29, 2019
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8
Tiny silica bottles filled with medicine and a special temperature-sensitive material could be used for drug delivery to kill malignant cells only in certain parts of the body, according to a study published recently by researchers ...
Bio & Medicine
Aug 15, 2019
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39
A gene called MYC has become one of the hottest targets for cancer researchers around the world. MYC is known to drive tumor growth in nearly all cancer types—but successfully targeting the gene has proven to be a challenge. ...
Biochemistry
Jul 8, 2019
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After 20 years of dedicated research, scientists have cracked the chemical code of an incredibly complex 'anti-tumour antibiotic' known to be highly effective against cancer cells as well as drug-resistant bacteria, and have ...
Biochemistry
Apr 24, 2019
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258
DNA is small. Really, really, small. So, when researchers want to study the structure of a single-stranded DNA, they can't just pull out their microscopes: they have to get creative.
Biotechnology
Mar 7, 2019
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6