Antibody-drug conjugates (ADCs), a complex covalently linking a potent cytotoxin onto the antibody, has attracted great interest as a novel biotherapeutic approach. Site-specific conjugation of potent payloads can improve ...
Biochemistry
Feb 8, 2022
0
36
Scientists at The University of Texas MD Anderson Cancer Center and Northwestern Medicine have identified natural extracellular vesicles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients that can block ...
Bio & Medicine
Jan 20, 2022
0
1205
Arthritis can keep a cat from doing many of the things that kitties love to do. But now there's hope: The first treatment to ease arthritis pain in cats has been approved by the U.S. Food and Drug Administration.
Veterinary medicine
Jan 13, 2022
0
7
Coronaviruses are slippery, and that makes it hard to create effective vaccines that provide long-term protection. Now, University of Connectiut (UConn) researchers have developed a new way to model the spike protein of the ...
Cell & Microbiology
Jan 11, 2022
0
7
Ultrabright light from the Advanced Photon Source continues to illuminate mysteries around coronaviruses and shape the vaccines and therapeutics protecting us against variants of concern.
Biochemistry
Dec 14, 2021
0
22
Researchers at Sandia have created a platform for discovering, designing and engineering novel antibody countermeasures for emerging viruses. This new process of screening for nanobodies that "neutralize" or disable the virus ...
Bio & Medicine
Dec 13, 2021
0
43
It is widely understood that antibodies neutralize viruses by latching onto their surfaces and blocking them from infecting host cells. But new research reveals that this barrier method isn't the only way that antibodies ...
Cell & Microbiology
Nov 30, 2021
0
606
Monoclonal antibody drugs are among the few treatments available for COVID, providing a lifeline for those at high risk of severe illness and hospitalization. However, the usefulness of these drugs is limited because they ...
Biotechnology
Nov 19, 2021
0
78
Challenging the dogma of what scientists thought they understood about DNA viruses, a team of researchers led by Children's Hospital of Philadelphia (CHOP) has shown that adenovirus uses its own efficient RNA splicing mechanisms ...
Molecular & Computational biology
Oct 21, 2021
0
68
No one knows why some people age worse than others and develop diseases -such as Alzheimer's, fibrosis, type 2 diabetes or some types of cancer- associated with this aging process. One explanation for this could be the degree ...
Cell & Microbiology
Oct 20, 2021
1
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