Related topics: antibiotics

Anthrax bacteria conspire with viruses to stay alive

(PhysOrg.com) -- The brute force of Bacillus anthracis, the ancient scourge that causes anthrax, can sweep through and overpower a two-ton animal in under 72 hours. But when it isn't busy claiming livestock and humans throughout ...

When dangerous toxins teach fundamental biology

"What our work shows is how a complex in the center of the cell, the ER-Golgi interaction region, controls plasma membrane cholesterol, which is essential for many cellular functions, if not essential for multicellular life," ...

Engineering an enzyme against antibiotic-resistant anthrax

In the 2001 "Amerithrax" attacks, anthrax-causing spores were sent through the mail to media outlets and members of Congress, sickening at least 22 people and killing five. Antibiotic-resistant strains of the bacteria are ...

Anthrax arms race helped Europeans evolve against disease

New research from the Cornell College of Veterinary Medicine has revealed how humans evolved greater resistance against anthrax multiple times during history: when they developed a diet of more ruminants, and when agricultural ...

Stripping down bacterial armor: A new way to fight anthrax

A new study led by Dr. Antonella Fioravanti in the lab of Prof. Han Remaut (VIB-VUB Center for Structural Biology) has shown that removing the armor of the bacterium that causes anthrax slows its growth and negatively affects ...

Genomic study of 412 anthrax strains provides new virulence clues

By analyzing genomic sequences from more than 400 strains of the bacterium that causes anthrax, researchers have provided the first evidence that the severity – technically known as virulence – of specific strains may ...

Anthrax: A hidden threat to wildlife in the tropics

Anthrax, a disease so far not associated with tropical rain forests, is common in the Ivory Coast's Taï National Park and is posing a serious threat to wildlife there. The bacterium could soon even cause the extinction of ...

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Anthrax

Anthrax is an acute disease caused by Bacillus anthracis. It affects both humans and animals and most forms of the disease are highly lethal. There are effective vaccines against anthrax, and some forms of the disease respond well to antibiotic treatment.

Like many other members of the genus Bacillus, Bacillus anthracis can form dormant spores that are able to survive in harsh conditions for extremely long periods of time—even decades or centuries. Such spores can be found on all continents, even Antarctica. When spores are inhaled, ingested, or come into contact with a skin lesion on a host they may reactivate and multiply rapidly.

Anthrax commonly infects wild and domesticated herbivorous mammals which ingest or inhale the spores while browsing—in fact, ingestion is thought to be the most common route by which herbivores contract anthrax. Carnivores living in the same environment may become infected by consuming infected animals. Diseased animals can spread anthrax to humans, either by direct contact (e.g. inoculation of infected blood to broken skin) or consumption of diseased animals' flesh.

Anthrax spores can be produced in vitro and used as a biological weapon. Anthrax does not spread directly from one infected animal or person to another, but spores can be transported by clothing or shoes and the body of an animal that died of anthrax can also be a source of anthrax spores.

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