News tagged with androgen receptors
Researchers discover a potential target for therapy for patients with a deadly prostate cancer
A monoclonal antibody targeting a well known cell surface protein inhibited prostate cancer growth and metastasis in an aggressive form of the disease that did not respond to hormone therapy, according to a study by researchers ...
Nov 08, 2010 |
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Study links normal function of protein, not its build up inside cells, to death of neurons
A study led by St. Jude Children's Research Hospital investigators links the muscle weakness and other symptoms of a rare neurodegenerative disease to a misstep in functioning of a normal protein, rather than its build-up ...
Medicine & Health / Neuroscience
Sep 22, 2010 |
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'Winner effect' linked to changes in brain circuitry, study finds
The next time the Brewers go on a road-trip skid, it might not be their fault. The "winner effect," in which animals that win a competition win subsequent ones, occurs because of changes in their brain's circuitry. Those ...
Jul 19, 2010 |
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Team finds new target for treatment of advanced prostate cancer
(PhysOrg.com) -- In its early stages, prostate cancer requires androgens (hormones that promote the development and maintenance of male sex characteristics) for growth, and current first-line therapies target ...
Jul 06, 2010 |
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Profiling prostate cancer
A large scale genetic analysis of multiple prostate cancer samples, published online by Cell Press on June 24th in the journal Cancer Cell, is providing exciting new insight into the disease and may lead to more effective treatm ...
Jun 24, 2010 |
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Male sex hormones in ovaries essential for female fertility
Male sex hormones, such as testosterone, have well defined roles in male reproduction and prostate cancer. What may surprise many is that they also play an important role in female fertility. A new study finds that the presence ...
Medicine & Health / Medical research
May 26, 2010 |
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Androgen receptor may explain male dominance in liver cancer
A University of Rochester study helps to explain why men get liver cancer more often than women and opens the door for a new treatment pathway, by showing a direct link between the androgen receptor, which is more active ...
May 19, 2010 |
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Gene fusions may be the 'smoking gun' in prostate cancer development
Prostate cancer treatments that target the hormone androgen and its receptor may be going after the wrong source, according to a new study. Researchers have found that when two genes fuse together to cause ...
May 18, 2010 |
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Testosterone directly amplifies but does not program male behaviors
New research uncovers some surprising information about how sex hormones control masculinization of the brain during development and drive gender related behaviors in adult males. The study, published by Cell Press in the ...
Medicine & Health / Neuroscience
Apr 28, 2010 |
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New targeted therapy effective in treating advanced prostate cancer
An experimental drug is showing promise for the treatment of men with an aggressive form of advanced prostate cancer. A new multicenter study has concluded that the targeted therapy MDV3100 is safe and effective for patients ...
Apr 14, 2010 |
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Protein central to being male plays key role in wound healing
A molecular receptor pivotal to the action of male hormones such as testosterone also plays a crucial role in the body's ability to heal, report scientists in the December issue of the Journal of Clinical Investigation.
Jan 04, 2010 |
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Random DNA mix-ups not so random in cancer development
Researchers at the UC San Diego School of Medicine have pinpointed a mechanism that may help explain how chromosomal translocations - the supposedly random shuffling of large chunks of DNA that frequently lead to cancer - ...
Dec 03, 2009 |
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Promising pharmaceutical agents emerge as sports doping products
Researchers from the German Sport University Cologne in Germany found that non-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) are being sold on the black market for their ...
Medicine & Health / Medications
Nov 19, 2009 |
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Mighty mice: Treatment targeted to muscle improves motor neuron disease
New research with transgenic mice reveals that a therapy directed at the muscle significantly improves disease symptoms of a genetic disorder characterized by destruction of the neurons that control movement. The study, published ...
Medicine & Health / Neuroscience
Aug 12, 2009 |
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Study reveals a reprogrammed role for the androgen receptor
The androgen receptor - a protein ignition switch for prostate cancer cell growth and division - is a master of adaptability. When drug therapy deprives the receptor of androgen hormones, thereby halting cell proliferation, ...
Jul 27, 2009 |
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