The androgen receptor is a key transcriptional factor for the proper sex development—especially in males—and the physiological balance of all the tissues that express this receptor. The androgen receptor is involved in ...
Biochemistry
Mar 16, 2023
0
16
Cytochrome P450, family 17, subfamily A, polypeptide 1 (cyp17a1) is a critical enzyme involved in gonadal steroidogenesis, including androgen and estrogen production. Among sex steroids, androgen signaling disruption is known ...
Plants & Animals
Apr 15, 2022
0
3
Rank in social hierarchy is a condition not solely claimed by humans. In the animal kingdom, male peacocks exhibit brightly colored plumes to illustrate dominance, and underwater, male fish show pops of bright colors to do ...
Evolution
Nov 10, 2020
0
1436
Chemists at Tokyo Tech's Laboratory for Chemistry and Life Science have designed and developed a capsule-shaped synthetic receptor that can distinguish between male and female steroid hormones. Namely, the receptor displays ...
Biochemistry
Apr 22, 2019
0
8
Sex-changing fish exhibit differences in androgen receptor (AR) expression in muscles that are highly sensitive to androgens (male sex hormones) and essential for male courtship behavior, according to a Georgia State University ...
Plants & Animals
Jun 8, 2017
0
6
Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure. In spite of the ...
Biochemistry
Aug 16, 2016
0
9
Knowledge of the minute details of the proteins that are linked to diseases is crucial if we are to discover therapeutic targets and thus pave the way for possible treatments. Such knowledge gains even more relevance when ...
Biochemistry
Jun 10, 2016
0
14
New research from a Wake Forest University biologist who studies animal behavior suggests that evolution is hard at work when it comes to the acrobatic courtship dances of a tropical bird species.
Plants & Animals
Apr 22, 2015
1
11
The androgen receptor in human cells inhibits fat accumulation, but its activity can be sabotaged by glucocorticoids, steroids that regulate fat deposition and are known drivers of obesity and insulin resistance, said researchers ...
Cell & Microbiology
Sep 20, 2012
0
0
The next time the Brewers go on a road-trip skid, it might not be their fault. The "winner effect," in which animals that win a competition win subsequent ones, occurs because of changes in their brain's circuitry. Those ...
Plants & Animals
Jul 19, 2010
0
0
