Amyloids refer to abnormal fibrous extracellular and proteinaceous deposits found in organs and tissues that form insoluble constructs that are resistant to degradation. Their formation can accompany disease, where each disease ...
Researchers at University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia. In a new study, published July 9, 2022 ...
Evolution
Jul 18, 2022
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503
It is now possible to deliver therapeutics based on short interfering RNAs to hepatocytes; however, new delivery solutions are necessary to target additional organs. In a new report now published in Nature Biotechnology, ...
Spider silk is said to be one of the strongest, toughest materials on the Earth. Now engineers at Washington University in St. Louis have designed amyloid silk hybrid proteins and produced them in engineered bacteria. The ...
Nanomaterials
Jul 21, 2021
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4555
Patients with type 1 diabetes have to regularly inject themselves with insulin, a hormone that helps their cells absorb glucose from the bloodstream. Another hormone called glucagon, which has the opposite effect, is given ...
Molecular & Computational biology
Jun 24, 2019
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1
Amyloids are clumps of protein fragments that stick together to form stringy fibrils such as the plaques seen in the brains of Alzheimer's patients. Many of these proteins bind to metals such as zinc, but the structure of ...
Materials Science
May 30, 2017
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227
In research that could one day lead to advances against neurodegenerative diseases like Alzheimer's and Parkinson's, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the ...
Bio & Medicine
Jan 17, 2017
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829
(Phys.org) —A team of researchers with members from Syracuse University and the University of California, has found that naturally forming peptides can self-assemble into catalysts. In their paper published in the journal ...
Biologists at UC San Diego have succeeded in genetically engineering algae to produce a complex and expensive human therapeutic drug used to treat cancer.
Cell & Microbiology
Dec 10, 2012
1
0
Researchers suspect that a protein superstructure called amyloid beta is responsible for much of the neural damage of Alzheimer's disease.
Biochemistry
Nov 9, 2010
0
0
