News tagged with amyloid beta proteins

Active compounds against Alzheimer's disease

More than half of all cases of dementia in the elderly can be attributed to Alzheimer's disease. Despite vast research efforts, an effective therapy has not been developed, and treatment consists of dealing with the symptoms. ...

Chemistry / Biochemistry

created Jan 12, 2012 | popularity 4 / 5 (1) | comments 0

Study of cerebrospinal fluid reveals potential new Alzheimer's gene

A genomic study of cerebrospinal fluid (CSF) has added a new gene to the list of potential genetic contributors to Alzheimer's disease, a national research team led by Indiana University School of Medicine ...

Medicine & Health / Neuroscience

created Dec 14, 2010 | popularity not rated yet | comments 0

Modulating a protein in the brain could help control Alzheimer's disease

A protein known to exist in the brain for more than 30 years, called 5-lipoxygenase, has been found to play a regulatory role in the formation of the amyloid beta in the brain, the major component of plaques implicated in ...

Medicine & Health / Neuroscience

created Nov 18, 2010 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Proteins linked to longevity also linked to Alzheimer's

Over the past 20 years, scientists have learned that proteins called sirtuins play a vital role in longevity and stress response in organisms as diverse as humans, yeast and mice. A new paper from MIT biologists ...

Medicine & Health / Medical research

created Jul 27, 2010 | popularity 4.8 / 5 (10) | comments 1 | with audio podcast

Researchers find dementia in diabetics differs from dementia in nondiabetics

Researchers from Mayo Clinic's Florida campus say that dementia in some diabetics appears to be caused often by vascular disease in the brain, and the dementia that develops in people without diabetes is more likely associated ...

Medicine & Health / Diseases, Conditions, Syndromes

created Jul 14, 2010 | popularity 5 / 5 (1) | comments 0

Protein inhibitor helps rid brain of toxic tau protein

Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University ...

Medicine & Health / Neuroscience

created Sep 29, 2009 | popularity 4.8 / 5 (5) | comments 0

Phase 3 Alzheimer's drug increases toxic beta amyloid in the brain -- but still provides benefits

New insights into how a Phase III Alzheimer's drug might work were among the advances in potential therapies targeting two abnormal brain proteins - beta amyloid and phosphorylated tau - that were reported today at the Alzheimer's ...

Medicine & Health / Diseases, Conditions, Syndromes

created Jul 15, 2009 | popularity not rated yet | comments 0

Alzheimer's research yields potential drug target

Scientists at UC Santa Barbara and several other institutions have found laboratory evidence that a cluster of peptides may be the toxic agent in Alzheimer's disease. Scientists say the discovery may lead ...

Chemistry / Biochemistry

created Jul 01, 2009 | popularity 5 / 5 (3) | comments 0

Variant form of amyloid beta hinders amyloidogenesis, development of Alzheimer's disease

Alzheimer's disease causes misfolding and aggregation of a protein fragment known as amyloid beta and its deposition as plaques in the brain. This process triggers a cascade of event that leads to neurodegeneration. A new ...

Medicine & Health / Neuroscience

created Mar 12, 2009 | popularity 4.5 / 5 (2) | comments 0

Forgotten and lost - when proteins 'shut down' our brain

(PhysOrg.com) -- Which modules of the tau protein, in neurons of Alzheimer disease patients, may act in a destructive manner were investigated by researchers from the Max Planck Institute for Biophysical Chemistry ...

Biology /

created Feb 17, 2009 | popularity 3.5 / 5 (4) | comments 0

New Pathway is a Common Thread in Age-Related Neurodegenerative Diseases

How are neurodegenerative diseases such as Alzheimer's initiated, and why is age the major risk factor? A recent study of a protein called MOCA (Modifier of Cell Adhesion), carried out at the Salk Institute ...

Medicine & Health / Medical research

created Jan 29, 2009 | popularity 5 / 5 (1) | comments 0