News tagged with alpha 1 antitrypsin
Gene therapy makes mice breath easier
Researchers from Boston University School of Medicine (BUSM) have discovered a new gene therapy that may prevent the progression of emphysema. The study, which appears on-line in the Journal of Clinical Investigation, descri ...
Medicine & Health / Medical research
Dec 21, 2009 |
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Gene variant heightens risk of severe liver disease in cystic fibrosis
Researchers at the University of North Carolina at Chapel Hill have discovered a genetic risk factor for severe liver disease in people with cystic fibrosis. Those who carry a particular variant of the SERPINA1 gene (also ...
Sep 08, 2009 |
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New genes at work in patients with hereditary lung disease
University of Florida researchers have safely given new, functional genes to patients with a hereditary defect that can lead to fatal lung and liver diseases, according to clinical trial findings slated to appear this week ...
Medicine & Health / Medical research
Aug 10, 2009 |
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Search results for alpha 1 antitrypsin
Researchers generate iPSCs to further treatments for lung disease
(Boston) A team of researchers from Boston University's Center for Regenerative Medicine and the Pulmonary Center have generated 100 new lines of human induced pluripotent stem cells (iPSC) from individuals with lung diseases, ...
Oct 28, 2010 |
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Secondhand smoke may provoke inflammatory response in lungs
Second-hand smoke is associated with a number of diseases and conditions, including cancer, heart disease, and emphysema. It is an irritant to lung tissue and blood vessels, but the processes through which the body reacts ...
Aug 26, 2010 |
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Recommendations for treatment of inherited lung disease are unjustified
An expensive treatment recommended for a genetic disorder called alpha-1 antitrypsin deficiency has no proven clinical benefit, according to a systematic review by Cochrane Researchers. The disorder causes chronic lung disease ...
Medicine & Health / Diseases, Conditions, Syndromes
Jul 06, 2010 |
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FDA approves trial for type 1 diabetes treatment
The U.S. Food & Drug Administration (FDA) has granted Investigational New Drug (IND) regulatory clearance to initiate a Phase I/II clinical trial evaluating Alpha-1 Antitrypsin (AAT) in type 1 diabetics, based on research ...
Medicine & Health / Medical research
Jun 29, 2010 |
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Commonly used seizure drug could treat severe genetic liver disease: study
The liver scarring of [alpha]1-antitrypsin (AT) deficiency, the most common genetic cause for which children undergo liver transplantation, might be reversed or prevented with a medication that has long been used to treat ...
Medicine & Health / Medical research
Jun 03, 2010 |
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New data emerges on liver transplant survival rates
Researchers at the University of Miami School of Medicine compared the outcomes of cirrhotic patients who underwent liver transplants for nonalcoholic steatohepatitis (NASH) versus alcoholic liver disease (ETOH) and found ...
Medicine & Health / Diseases, Conditions, Syndromes
Nov 25, 2009 |
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Key to pre-eclampsia may be found in misfolded proteins in the urine
Clues to the cause of preeclampsia, a common, but serious hypertension complication of pregnancy that has puzzled doctors and researchers for decades, point to proteins that misfold and aggregate, according to Yale School ...
Medicine & Health / Medical research
Jan 30, 2009 |
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Well-known drug (AAT) could overcome obstacles to islet transplantation
Researchers from Ben-Gurion University of the Negev (BGU) in Beer-Sheva, Israel have demonstrated that treating diabetic animals with alpha-1-antitrypsin (AAT) following an islet transplantation procedure eliminates the inflammation ...
Medicine & Health / Medical research
Oct 30, 2008 |
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AAT protein restores blood glucose in type 1 diabetes model
A protein made by the liver in response to inflammation and used to treat patients suffering from a genetic form of emphysema has been shown to restore blood glucose levels in a mouse model of Type 1 diabetes mellitus, according ...
Medicine & Health / Medical research
Oct 14, 2008 |
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Researchers find common gene disorder doubles risk of lung cancer, even among nonsmokers
Mayo Clinic researchers have found that carrying a common genetic disorder doubles the risk of developing lung cancer in smokers and nonsmokers. The study is published in the May 26 issue of the Archives of Internal Medicine, a jour ...
Medicine & Health / Medical research
May 27, 2008 |
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List of search results for alpha 1 antitrypsin
