Brain receptor pulls open electrical gate like a puppet master

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain ...

Biophysicists reveal how optogenetic tool works

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state. The discovery provides a description of the mechanism behind the light-driven ...

The face of a mouse reveals its emotions: study

Researchers at the Max Planck Institute of Neurobiology are the first to describe emotional facial expressions for mice. Similar to humans, mouse facial expressions change when it tastes something sweet or bitter, or when ...

Cryo-electron microscopy characterizes integrins

A collaboration between three labs at UC San Francisco has resulted in an unprecedented look at a member of a vital and ubiquitous class of proteins called integrins (pronounced "INT-uh-grins"). Integrins are associated with ...

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