News tagged with abnormal protein

Researchers identify potential molecular target to prevent growth of cancer cells

Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of ...

Chemistry / Biochemistry

created Sep 16, 2011 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Scientists uncover role for cell scaffold in tumor formation

A group of scientists at the Instituto Gulbenkian de Ciencia, in Portugal, have uncovered a surprising link between the cell's skeleton and organ size. The team, led by Florence Janody, show in the journal ...

Biology / Cell & Microbiology

created Jun 06, 2011 | popularity not rated yet | comments 0

Researchers find drug that stops progression of Parkinson's disease in mice

In a major breakthrough in the battle against Parkinson's disease, researchers at the University of Colorado School of Medicine have discovered a drug that stops the progression of the degenerative illness in mice and is ...

Chemistry / Biochemistry

created Mar 08, 2011 | popularity 5 / 5 (1) | comments 0

UMMS and Lundbeck to explore potential targeted therapy for Huntington's disease

The University of Massachusetts Medical School (UMMS) and Lundbeck Inc. today announced a research collaboration aimed at further development of a targeted therapy to slow or halt the progression of Huntington's disease (HD).

Medicine & Health / Medical research

created Jan 28, 2011 | popularity not rated yet | comments 0

'Smart drug' targets new mutation, dramatically shrinks aggressive sarcoma and lung cancer

A new oral drug caused dramatic shrinkage of a patient's rare, aggressive form of soft-tissue cancer that was driven by an abnormally activated protein, physician-scientists from Dana-Farber Cancer Institute report in the ...

Medicine & Health / Cancer

created Oct 27, 2010 | popularity 5 / 5 (1) | comments 0

One step closer in finding treatment for amyloidosis

University College London scientists funded by the Medical Research Council (MRC) have devised a new approach to treatment of amyloidosis, according to new research published yesterday in Nature.

Medicine & Health / Medical research

created Oct 21, 2010 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Researchers create first molecule blocks key component of cancer genes' on-off switch

In the quest to arrest the growth and spread of tumors, there have been many attempts to get cancer genes to ignore their internal instruction manual. In a new study, a team led by Dana-Farber Cancer Institute scientists ...

Medicine & Health / Cancer

created Sep 24, 2010 | popularity 5 / 5 (11) | comments 1 | with audio podcast

The rare aging disease, Progeria, linked to aging in the general population

Progeria, also known as Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare, fatal genetic disease characterized by an appearance of accelerated aging in children. All children with Progeria die of the same heart disease ...

Medicine & Health / Diseases, Conditions, Syndromes

created Sep 07, 2010 | popularity 5 / 5 (1) | comments 0

Cardiac biomarker indicates fluid overload in dialysis patients

Nephrologists must consider fluid overload effects when prescribing dialysis, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The fluid overload biomar ...

Medicine & Health / Diseases, Conditions, Syndromes

created May 27, 2010 | popularity 1 / 5 (1) | comments 0

Ultrasound enhances noninvasive Down syndrome tests

The addition of a "genetic sonogram" maximizes the accuracy of non-invasive testing for Down syndrome, said a Baylor College of Medicine researcher who was lead author of a landmark study in the current issue of Obstetrics an ...

Medicine & Health / Diseases, Conditions, Syndromes

created Nov 20, 2009 | popularity not rated yet | comments 0

Protein linked to mental retardation controls synapse maturation, plasticity

A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated the mechanism by which a signaling protein found throughout the brain controls the maturation and strength of excitatory synapses, the tiny ...

Medicine & Health / Neuroscience

created Jun 01, 2009 | popularity not rated yet | comments 0

Heart protein regulates blood vessel maintenance

Researchers identify a protein that regulates the physical state of blood vessels. The biochemical processes involved in this regulation are important in the study of cardiovascular health.

Chemistry / Biochemistry

created May 11, 2009 | popularity 5 / 5 (1) | comments 0

New target identified for potential treatment of retinopathy in premature babies

Results of a study in mice by researchers at the University of California, San Diego strongly suggest that the protein kinase JNK1 plays a key role in the development of retinopathy in premature infants. Their findings, ...

Medicine & Health / Medical research

created May 04, 2009 | popularity not rated yet | comments 0

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality ...

Medicine & Health / Genetics

created Apr 09, 2009 | popularity not rated yet | comments 0

Modification of mutant huntingtin protein increases its clearance from brain cells

A new study has identified a potential strategy for removing the abnormal protein that causes Huntington's disease (HD) from brain cells, which could slow the progression of the devastating neurological disorder. In the ...

Medicine & Health / Medical research

created Apr 02, 2009 | popularity 5 / 5 (3) | comments 0